Use of magnetic fields and nanoparticles to trigger drug release and improve tumor targeting

JF Liu, B Jang, D Issadore… - Wiley Interdisciplinary …, 2019 - Wiley Online Library
Drug delivery strategies aim to maximize a drug's therapeutic index by increasing the
concentration of drug at target sites while minimizing delivery to off‐target tissues. Because …

Dark-field/hyperspectral microscopy for detecting nanoscale particles in environmental nanotoxicology research

R Fakhrullin, L Nigamatzyanova… - Science of The Total …, 2021 - Elsevier
Nanoscale contaminants (including engineered nanoparticles and nanoplastics) pose a
significant threat to organisms and environment. Rapid and non-destructive detection and …

[HTML][HTML] Nanoplastics: From tissue accumulation to cell translocation into Mytilus galloprovincialis hemocytes. resilience of immune cells exposed to nanoplastics and …

M Sendra, A Saco, MP Yeste, A Romero… - Journal of hazardous …, 2020 - Elsevier
Plastic litter is an issue of global concern. In this work Mytilus galloprovincialis was used to
study the distribution and effects of polystyrene nanoplastics (PS NPs) of different sizes (50 …

Engineering nanoparticles toward the modulation of emerging cancer immunotherapy

S Wang, Z Sun, Y Hou - Advanced Healthcare Materials, 2021 - Wiley Online Library
Cancer immunotherapy is a new therapeutic strategy to fight cancer by activating the
patients' own immune system. At present, immunotherapy approaches such as cancer …

Targeting specific cells in the brain with nanomedicines for CNS therapies

F Zhang, YA Lin, S Kannan, RM Kannan - Journal of Controlled Release, 2016 - Elsevier
Abstract Treatment of Central Nervous System (CNS) disorders still remains a major clinical
challenge. The Blood–Brain Barrier (BBB), known as the major hindrance, greatly limits …

Magnetic nanostructures as emerging therapeutic tools to boost anti-tumour immunity

S Persano, P Das, T Pellegrino - Cancers, 2021 - mdpi.com
Simple Summary Immunotherapy represents an attractive therapeutic option for effective
treatment of different forms of cancers. However, many patients exhibit primary or acquired …

Fabrication of Curcumin Diethyl γ-Aminobutyrate-Loaded Chitosan-Coated Magnetic Nanocarriers for Improvement of Cytotoxicity against Breast Cancer Cells

S Hansapaiboon, BP Bulatao, FN Sorasitthiyanukarn… - Polymers, 2022 - mdpi.com
This study shows the effectiveness of magnetic-guide targeting in the delivery of curcumin
diethyl γ-aminobutyrate (CUR-2GE), a prodrug of curcumin (CUR) previously synthesized to …

Oxaliplatin–biomimetic magnetic nanoparticle assemblies for colon cancer-targeted chemotherapy: An in vitro study

Y Jabalera, B Garcia-Pinel, R Ortiz, G Iglesias… - Pharmaceutics, 2019 - mdpi.com
Conventional chemotherapy against colorectal cancer (CRC), the third most common cancer
in the world, includes oxaliplatin (Oxa) which induces serious unwanted side effects that limit …

Focusing light inside scattering media with magnetic-particle-guided wavefront shaping

H Ruan, T Haber, Y Liu, J Brake, J Kim, JM Berlin… - Optica, 2017 - opg.optica.org
Optical scattering has traditionally limited the ability to focus light inside scattering media
such as biological tissue. Recently developed wavefront shaping techniques promise to …

Formulation and in vitro evaluation of magnetoliposomes as a potential nanotool in colorectal cancer therapy

C Lorente, L Cabeza, B Clares, R Ortiz… - Colloids and Surfaces B …, 2018 - Elsevier
Magnetoliposomes (MLPs) offer many new possibilities in cancer therapy and diagnosis,
including the transport of antitumor drugs, hyperthermia treatment, detection using imaging …