Neuromesodermal progenitors and the making of the spinal cord

D Henrique, E Abranches, L Verrier… - Development, 2015 - journals.biologists.com
Neuromesodermal progenitors (NMps) contribute to both the elongating spinal cord and the
adjacent paraxial mesoderm. It has been assumed that these cells arise as a result of …

Symmetry breaking, germ layer specification and axial organisation in aggregates of mouse embryonic stem cells

SC Van den Brink, P Baillie-Johnson, T Balayo… - …, 2014 - journals.biologists.com
Mouse embryonic stem cells (mESCs) are clonal populations derived from preimplantation
mouse embryos that can be propagated in vitro and, when placed into blastocysts …

Dawn of the organoid era: 3D tissue and organ cultures revolutionize the study of development, disease, and regeneration

N Akkerman, LHK Defize - Bioessays, 2017 - Wiley Online Library
Novel and updated approaches of culturing cells in 3D are rapidly advancing our
understanding of development, health, and disease. As tissues have been found to behave …

Wnt/β-catenin and FGF signalling direct the specification and maintenance of a neuromesodermal axial progenitor in ensembles of mouse embryonic stem cells

DA Turner, PC Hayward, P Baillie-Johnson… - …, 2014 - journals.biologists.com
The development of the central nervous system is known to result from two sequential
events. First, an inductive event of the mesoderm on the overlying ectoderm that generates a …

Generation of aggregates of mouse embryonic stem cells that show symmetry breaking, polarization and emergent collective behaviour in vitro

P Baillie-Johnson, SC Van den Brink, T Balayo… - JoVE (Journal of …, 2015 - jove.com
We have developed a protocol improving current Embryoid Body (EB) culture which allows
the study of self-organization, symmetry breaking, axial elongation and cell fate specification …

Morphology‐based mammalian stem cell tests reveal potential developmental toxicity of donepezil

CGY Lau, Y Marikawa - Molecular reproduction and …, 2014 - Wiley Online Library
Various compounds, including therapeutic drugs, can adversely impact the survival and
development of embryos in the uterus. Identification of such development‐interfering agents …

Nível de desidratação voluntária de dois lagartos de forrageamentos distintos em uma área de Caatinga do Estado de Pernambuco, Brasil

PMA OLIVEIRA - 2021 - repositorio.ufpe.br
Lagartos possuem alta sensibilidade a temperaturas extremas por serem animais que
dependem do ambiente para regular sua temperatura corpórea. E nos répteis, a exposição …