Mendelian randomisation (MR) studies allow a better understanding of the causal effects of
modifiable exposures on health outcomes, but the published evidence is often hampered by …

Importance In light of increasing cannabis use among pregnant women, the US Surgeon
General recently issued an advisory against the use of marijuana during pregnancy …

Psychiatric diseases exact a heavy socioeconomic toll, and it is particularly difficult to identify
their risk factors and causative mechanisms due to their multifactorial nature, the limited …

Importance Anxiety and stress-related disorders are among the most common mental
disorders. Although family and twin studies indicate that both genetic and environmental …

Importance Cannabis use and potency of cannabis have increased during the past 2
decades. If the association between cannabis use and schizophrenia is causal, this should …

Importance Psychosis is a hypothesized consequence of cannabis use. Legalization of
cannabis could therefore be associated with an increase in rates of health care utilization for …

a robust association between cannabis use, heavy use, and misuse with future risk of
schizophrenia. 1-3 Despite adjusting for covariates, including current psychotic symptoms …

Eating disorders and substance use disorders frequently co‐occur. Twin studies reveal
shared genetic variance between liabilities to eating disorders and substance use, with the …

Introduction There is increasing interest in the relationship between cannabinoids and
psychosis. While individual human laboratory studies have been critical in demonstrating …

Importance Although hypothesis-driven research has identified several factors associated
with psychosis, this one-exposure-to-one-outcome approach fails to embrace the multiplicity …