Background: β-thalassaemia is a disorder caused by mutations in the β-globin gene, leading
to defective production of haemoglobins (Hb) and red blood cells (RBCs). It is characterised …

Background ß-thalassemia is one of the most common inherited blood disorders in the world
and a major deterrent to the public health of Bangladesh. The management of thalassemia …

Thalassemia is identified as a prevalent disease in Malaysia, known to be one of the
developing countries. Fourteen patients with confirmed cases of thalassemia were recruited …

Both α-and β-thalassaemia syndromes are public health problems in the multi-ethnic
population of Malaysia. To molecularly characterise the α-and β-thalassaemia deletions and …

Beta-thalassemia is one of the most prevalent inherited diseases and a public health
problem in Malaysia. Malaysia is geographically divided into West and East Malaysia. In …

Thalassaemia is a public health problem in Malaysia, with each ethnic group having their
own common mutations. However, there is a lack on data on the prevalence and common …

Background: Thalassemia is a prevalent condition characterized by decreased production or
absence of hemoglobin globin chains. There are 2 types of thalassemia, alpha thalassemia …

Background Bangladesh lies in the global thalassemia belt, which has a defined mutational
hot-spot in the beta-globin gene. The high carrier frequencies of beta-thalassemia trait and …

β-Thalassemia is a public health problem where 4.5% of Malaysians are β-thalassemia
carriers. The genetic disorder is caused by defects in the β-globin gene complex which lead …

Haemoglobin (Hb) E is the most common Hb variant found among Southeast Asian
populations. Myanmar also has high prevalence of important haemoglobinopathies: Hb E-1 …