Amentoflavone derivatives significantly act towards the main protease (3CLPRO/MPRO) of SARS-CoV-2: in silico admet profiling, molecular docking, molecular …
SARS-CoV-2 is the foremost culprit of the novel coronavirus disease 2019 (nCoV-19 and/or
simply COVID-19) and poses a threat to the continued life of humans on the planet and …
simply COVID-19) and poses a threat to the continued life of humans on the planet and …
Synthesis, antimicrobial, molecular docking and molecular dynamics studies of lauroyl thymidine analogs against SARS-CoV-2: POM study and identification of the …
Nucleoside precursors and nucleoside analogs occupy an important place in the treatment
of viral respiratory pathologies, especially during the current COVID-19 pandemic. From this …
of viral respiratory pathologies, especially during the current COVID-19 pandemic. From this …
Natural flavonoids effectively block the CD81 receptor of hepatocytes and inhibit HCV infection: A computational drug development approach
Hepatitis C virus (HCV) infection is a major public health concern, and almost two million
people are infected per year globally. This is occurred by the diverse spectrum of viral …
people are infected per year globally. This is occurred by the diverse spectrum of viral …
Missense mutations in spike protein of SARS‐CoV‐2 delta variant contribute to the alteration in viral structure and interaction with hACE2 receptor
TB Mahmood, MI Hossan, S Mahmud… - Immunity …, 2022 - Wiley Online Library
Introduction Many of the global pandemics threaten human existence over the decades
among which coronavirus disease (COVID‐19) is the newest exposure circulating …
among which coronavirus disease (COVID‐19) is the newest exposure circulating …
Molecular docking and dynamics studies to explore effective inhibitory peptides against the spike receptor binding domain of SARS-CoV-2
The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become
a pandemic due to the high transmission and mortality rate of this virus. The world health …
a pandemic due to the high transmission and mortality rate of this virus. The world health …
Design of Multi-Epitope Vaccine for Staphylococcus saprophyticus: Pan-Genome and Reverse Vaccinology Approach
Staphylococcus saprophyticus is a Gram-positive coccus responsible for the occurrence of
cystitis in sexually active, young females. While effective antibiotics against this organism …
cystitis in sexually active, young females. While effective antibiotics against this organism …
Integrating Reinforcement Learning and Monte Carlo Tree Search for enhanced neoantigen vaccine design
Y Lin, J Ma, H Yuan, Z Chen, X Xu… - Briefings in …, 2024 - academic.oup.com
Recent advances in cancer immunotherapy have highlighted the potential of neoantigen-
based vaccines. However, the design of such vaccines is hindered by the possibility of weak …
based vaccines. However, the design of such vaccines is hindered by the possibility of weak …
Molecular Docking and In Silico Simulation of Trichinella spiralis Membrane‐Associated Progesterone Receptor Component 2 (Ts-MAPRC2) and Its Interaction with …
Background. Trichinellosis is a foodborne zoonotic disease caused by Trichinella spp.,
including Trichinella spiralis. This parasitic disease ranks as seven of the most infectious in …
including Trichinella spiralis. This parasitic disease ranks as seven of the most infectious in …
Immunoinformatics-Driven Strategies for Advancing Epitope-Based Vaccine Design for West Nile Virus
Abstract The West Nile virus (WNV) is the causative agent of West Nile disease (WND),
which poses a potential risk of meningitis or encephalitis. The aim of the study was to design …
which poses a potential risk of meningitis or encephalitis. The aim of the study was to design …
Synaptic vesicle protein 2 A mitigates parthanatos via apoptosis‐inducing factor in a rat model of pharmacoresistant epilepsy
C Li, Z Wang, M Ren, S Ren, G Wu… - CNS Neuroscience & …, 2024 - Wiley Online Library
Aims Synaptic vesicle protein 2A (SV2A) is a unique therapeutic target for
pharmacoresistant epilepsy (PRE). As seizure‐induced neuronal programmed death …
pharmacoresistant epilepsy (PRE). As seizure‐induced neuronal programmed death …