MicroRNAs (miRNAs) are a class of small, well-conserved noncoding RNAs that regulate
gene expression post-transcriptionally. They have been demonstrated to regulate a lot of …

Neurodevelopmental disorders (NDDs) are characterized by aberrant and delayed early-life
development of the brain, leading to deficits in language, cognition, motor behaviour and …

Currently, many studies on neuropsychiatric disorders have utilized massive trio-based
whole-exome sequencing (WES) and whole-genome sequencing (WGS) to identify …

Many neurodegenerative diseases, such as Alzheimer's disease, Parkinson disease,
vascular and frontotemporal dementias, as well as other chronic neurological pathologies …

Plasma microRNAs (miRNAs) have been proposed as potential biomarkers in Alzheimer's
disease (AD). Here, we explored their use as early sensors of the preclinical phase of the …

The human genome encodes a vast repertoire of protein non-coding RNAs (ncRNA), some
specific to the brain. MicroRNAs, which interfere with the translation of target mRNAs, are of …

Emerging evidence has shown that noncoding RNAs, particularly microRNAs (miRNAs),
contribute to the pathogenesis of mood and anxiety disorders, although the molecular …

Depression and anxiety are devastating disorders. Understanding the mechanisms that
underlie the development of depression and anxiety can provide new hints on novel …

Bipolar disorder (BP) is a chronic neuropsychiatric condition characterized by pathological
fluctuations in mood from mania to depression. Adoption, twin and family studies have …

Suicide is a major public health concern. A significant proportion of depressed individuals
show suicidal ideation. The currently available medications are not optimal and a large …