Herpesvirus latency

JI Cohen - The Journal of clinical investigation, 2020 - Am Soc Clin Investig
Herpesviruses infect virtually all humans and establish lifelong latency and reactivate to
infect other humans. Latency requires multiple functions: maintaining the herpesvirus …

The interplay between viral-derived miRNAs and host immunity during infection

R Mishra, A Kumar, H Ingle, H Kumar - Frontiers in immunology, 2020 - frontiersin.org
MicroRNAs are short non-coding RNAs that play a crucial role in the regulation of gene
expression during cellular processes. The host-encoded miRNAs are known to modulate the …

Viruses, microRNAs, and host interactions

RL Skalsky, BR Cullen - Annual review of microbiology, 2010 - annualreviews.org
One of the most significant recent advances in biomedical research has been the discovery
of the∼ 22-nt-long class of noncoding RNAs designated microRNAs (miRNAs). These …

[HTML][HTML] Virus-encoded microRNAs

A Grundhoff, CS Sullivan - Virology, 2011 - Elsevier
MicroRNAs (miRNAs) are the subject of enormous interest. They are small non-coding
RNAs that play a regulatory role in numerous and diverse cellular processes such as …

Herpes keratitis

AM Rowe, AJS Leger, S Jeon, DK Dhaliwal… - Progress in retinal and …, 2013 - Elsevier
Herpes simplex virus-1 (HSV-1) infects the majority of the world's population. These
infections are often asymptomatic, but ocular HSV-1 infections cause multiple pathologies …

MicroRNA involvement in signaling pathways during viral infection

MG Barbu, CE Condrat, DC Thompson… - Frontiers in cell and …, 2020 - frontiersin.org
The study of miRNAs started in 1993, when Lee et al. observed their involvement in the
downregulation of a crucial protein known as LIN-14 in the nematode Caenorhabditis …

The molecular basis of herpes simplex virus latency

MP Nicoll, JT Proença… - FEMS microbiology …, 2012 - academic.oup.com
Herpes simplex virus type 1 is a neurotropic herpesvirus that establishes latency within
sensory neurones. Following primary infection, the virus replicates productively within …

Coxsackievirus B3 replication and pathogenesis

FS Garmaroudi, D Marchant, R Hendry, H Luo… - Future …, 2015 - Taylor & Francis
Viruses such as coxsackievirus B3 (CVB3) are entirely host cell-dependent parasites.
Indeed, they must cleverly exploit various compartments of host cells to complete their life …

The role of RNAi and microRNAs in animal virus replication and antiviral immunity

JL Umbach, BR Cullen - Genes & development, 2009 - genesdev.cshlp.org
The closely related microRNA (miRNA) and RNAi pathways have emerged as important
regulators of virus–host cell interactions. Although both pathways are relatively well …

MicroRNAs as mediators of viral evasion of the immune system

BR Cullen - Nature immunology, 2013 - nature.com
Cellular microRNAs serve key roles in the post-transcriptional regulation of almost every
cellular gene-regulatory pathway, and it therefore is not surprising that viruses have found …