In 2000, the third member of the globin family was discovered in human and mouse brain
and named neuroglobin (Ngb). Ngb is a monomeric 3/3 globin structurally similar to …

Nitric oxide (NO) regulates large swaths of animal physiology including wound healing,
vasodilation, memory formation, odor detection, sexual function, and response to infectious …

Impaired mitophagy is a primary pathogenic event underlying diverse aging-associated
diseases such as Alzheimer and Parkinson diseases and sarcopenia. Therefore …

The standard reference Caenorhabditis elegans strain, N2, has evolved marked behavioral
changes in social feeding behavior since its isolation from the wild. We show that the causal …

Pathogen avoidance behaviour has been observed across animal taxa as a vital host-
microbe interaction mechanism. The nematode Caenorhabditis elegans has evolved …

While the biological role of nitric oxide (NO) synthase (NOS) is appreciated, several
fundamental aspects of the NOS/NO-related signaling pathway (s) remain incompletely …

Abstract Background Nuclear receptors (NRs) can regulate gene expression; therefore, they
are classified as transcription factors. Despite the extensive research carried out on NRs, still …

Biological systems consist of multiple components of different physical and chemical
properties that require complex and dynamic regulatory loops to function efficiently. The …

Iron is vital for the life of most organisms. However, when dysregulated, iron can catalyze the
formation of oxygen (O 2) radicals that can destroy any biological molecule and thus lead to …

Oxygen (O2) homeostasis is important for all aerobic animals. However, the manner by
which O2 sensing and homeostasis contribute to lifespan regulation is poorly understood …