Pushing the natural frontier: Progress on the integration of biomaterial cues toward combinatorial biofabrication and tissue engineering

CF Guimarães, AP Marques, RL Reis - Advanced Materials, 2022 - Wiley Online Library
The engineering of fully functional, biological‐like tissues requires biomaterials to direct
cellular events to a near‐native, 3D niche extent. Natural biomaterials are generally seen as …

CAR T cell locomotion in solid tumor microenvironment

DT Nguyen, E Ogando-Rivas, R Liu, T Wang, J Rubin… - Cells, 2022 - mdpi.com
The promising outcomes of chimeric antigen receptor (CAR) T cell therapy in hematologic
malignancies potentiates its capability in the fight against many cancers. Nevertheless, this …

Mechanical properties of cell-and microgel bead-laden oxidized alginate-gelatin hydrogels

T Distler, L Kretzschmar, D Schneidereit… - Biomaterials …, 2021 - pubs.rsc.org
3D-printing technologies, such as biofabrication, capitalize on the homogeneous distribution
and growth of cells inside biomaterial hydrogels, ultimately aiming to allow for cell …

A Functional Hydrogel Bead-Based High-Throughput Screening System for Mammalian Cells with Enhanced Secretion of Therapeutic Antibodies

DA Wulandari, K Tsuru, K Minamihata… - ACS Biomaterials …, 2023 - ACS Publications
Droplet-based high-throughput screening systems are an emerging technology that
provides a quick test to screen millions of cells with distinctive characteristics …

Bioconjugation of COL1 protein on liquid-like solid surfaces to study tumor invasion dynamics

DT Nguyen, DI Pedro, A Pepe, JG Rosa, JI Bowman… - …, 2023 - pubs.aip.org
Tumor invasion is likely driven by the product of intrinsic and extrinsic stresses, reduced
intercellular adhesion, and reciprocal interactions between the cancer cells and the …

[HTML][HTML] Acquired demyelination but not genetic developmental defects in myelination leads to brain tissue stiffness changes

D Eberle, G Fodelianaki, T Kurth, A Jagielska… - Brain Multiphysics, 2020 - Elsevier
Abstract Changes in axonal myelination are an important hallmark of aging and a number of
neurological diseases. Demyelinated axons are impaired in their function and degenerate …

Processing of fast-gelling hydrogel precursors in microfluidics by electrocoalescence of reactive species

N Hauck, TA Neuendorf, MJ Männel, L Vogel, P Liu… - Soft Matter, 2021 - pubs.rsc.org
Microscopic hydrogels, also referred to as microgels, find broad application in life and
materials science. A well-established technique for fabricating uniform microgels is droplet …

Cell viscosity influences hematogenous dissemination and metastatic extravasation of tumor cells

V Gensbittel, G Follain, L Bochler, K Uhlmann… - bioRxiv, 2024 - biorxiv.org
Metastases arise from a multi-step process during which tumor cells change their mechanics
in response to microenvironmental cues. While such mechanical adaptability could …

Controlled Fabrication of Bioactive Microtubes for Screening Anti-Tongue Squamous Cell Migration Drugs

R Tang, L Yang, L Shen, X Ma, Y Gao, Y Liu… - Frontiers in …, 2022 - frontiersin.org
The treatment of tongue squamous cell carcinoma (TSCC) faces challenges because TSCC
has an aggressive biological behavior and manifests usually as widespread metastatic …

[图书][B] Granular hydrogel matrices with tunable plastic deformation properties for tissue engineering

J Reeves - 2022 - search.proquest.com
Understanding the complex behaviour of cells in 3D culture environments requires control
and knowledge of the mechanical and chemical signals they are receiving. While naturally …