Brain edema is considered as a common feature associated with hepatic encephalopathy
(HE). However, its central role as cause or consequence of HE and its implication in the …

Hepatic encephalopathy (HE) is a frequent complication of chronic liver disease (CLD) and
has a complex pathogenesis. Several preclinical and clinical studies have reported the …

Abstract Background & Aims Ammonia levels predicted hospitalisation in a recent landmark
study not accounting for portal hypertension and systemic inflammation severity. We …

Hepatic encephalopathy (HE) is a common complication of liver cirrhosis, associated with
high morbidity and mortality, for which no brain-targeted therapies exist at present. The …

Malnutrition and low dietary protein intake could be risk factors for developing peripheral
and central hyperammonemia, especially in pediatrics. Both curcumin and resveratrol …

Patients with liver disease are prone to various cognitive impairments. It is undeniable that
cognitive impairment is often regulated by both the nervous system and the immune system …

Ammonia levels are orchestrated by a series of complex interrelated pathways in which the
urea cycle has a central role. Liver dysfunction leads to an accumulation of ammonia, which …

Background and objectives: Postoperative cognitive dysfunction (POCD) represents a
decreased cognitive performance in patients undergoing general anesthesia for major …

Objective There is a lack of information on the molecular mechanisms by which steroid
hormones (testosterone, estrogen, and progesterone) regulate cognitive impairment. Thus …

Aims Hepatocytes resume proliferation following liver injuries to compensate for the loss of
liver mass. Robust liver regeneration is an intrinsic and pivotal process that facilitates …