Traumatic injury is a common cause of coagulopathy, primarily due to blood loss and
hemodilution secondary to fluid resuscitation. Traumatic injury-associated coagulopathy …

Heterotopic ossification (HO) is a pathological phenomenon in which ectopic lamellar bone
forms in soft tissues. HO involves many predisposing factors, including congenital and …

Cardiolipin (CL) is an anionic phospholipid located exclusively in the mitochondrial inner
membrane. Its presence in blood indicates mitochondrial damage and release from injured …

Background Both intracranial pressure (ICP) and the cerebrovascular pressure reactivity
represent the dysregulation of pathways directly involved in traumatic brain injury (TBI) …

A unique coagulopathy often manifests following traumatic brain injury, leading the clinician
down a difficult decision path on appropriate prophylaxis and therapy. Conventional …

The Joint Theater Trauma System (JTTS) was established in 2004 under US Central
Command to effect trauma care performance improvement on the battlefield to provide a …

Traumatic brain injury (TBI) is increasingly a major cause of disability across the globe. The
current methods of diagnosis are inadequate at classifying patients and prognosis. TBI is a …

Mild traumatic brain injury (mTBI) is a common, although poorly-defined clinical entity.
Despite its initially mild presentation, patients with mTBI can rapidly deteriorate, often due to …

Background Coagulopathy in traumatic brain injury (TBI) occurs frequently and is associated
with poor outcomes. Conventional coagulation assays (CCA) traditionally used to diagnose …

Traumatic brain injury (TBI) is a major cause of morbidity and mortality. Identifying factors
relevant to outcome can provide a better understanding of TBI pathophysiology, in addition …