Executive summary Traumatic brain injury (TBI) has the highest incidence of all common
neurological disorders, and poses a substantial public health burden. TBI is increasingly …

Traumatic brain injury (TBI) remains one of the most fatal and debilitating conditions in the
world. Current clinical management in severe TBI patients is mainly concerned with …

Background The effect of a liberal transfusion strategy as compared with a restrictive
strategy on outcomes in critically ill patients with traumatic brain injury is unclear. Methods …

When the fourth edition of the Brain Trauma Foundation's Guidelines for the Management of
Severe Traumatic Brain Injury were finalized in late 2016, it was known that the results of the …

Intracranial pressure (ICP) monitoring is now viewed as integral to the clinical care of many
life-threatening brain insults, such as severe traumatic brain injury, subarachnoid …

Background Acute treatment of cerebral edema and elevated intracranial pressure is a
common issue in patients with neurological injury. Practical recommendations regarding …

Traumatic brain injury (TBI) is the most common cause of death and disability in those aged
under 40 years in the UK. Higher rates of morbidity and mortality are seen in low-income …

Background The indications for intracranial pressure (ICP) monitoring in patients with acute
brain injury and the effects of ICP on patients' outcomes are uncertain. The aims of this study …

Managing traumatic brain injury (TBI) patients with a cerebral perfusion pressure (CPP) near
to the cerebral autoregulation (CA)-guided “optimal” CPP (CPPopt) value is associated with …

China has more patients with traumatic brain injury (TBI) than most other countries in the
world, making this condition a major public health concern. Population-based mortality of …