Varied Pathways of Infant Gut-Associated Bifidobacterium to Assimilate Human Milk Oligosaccharides: Prevalence of the Gene Set and Its Correlation with …

M Sakanaka, A Gotoh, K Yoshida, T Odamaki… - Nutrients, 2019 - mdpi.com
The infant's gut microbiome is generally rich in the Bifidobacterium genus. The mother's milk
contains natural prebiotics, called human milk oligosaccharides (HMOs), as the third most …

Human milk oligosaccharides and infant gut microbiota: Molecular structures, utilization strategies and immune function

B Zhang, LQ Li, F Liu, JY Wu - Carbohydrate Polymers, 2022 - Elsevier
Human milk oligosaccharides (HMOs) are a unique class of non-digestible carbohydrates
present in the mother milk, which play a key role in the development of infant gut microbiota …

Human milk glycobiome and its impact on the infant gastrointestinal microbiota

AM Zivkovic, JB German… - Proceedings of the …, 2011 - National Acad Sciences
Human milk contains an unexpected abundance and diversity of complex oligosaccharides
apparently indigestible by the developing infant and instead targeted to its cognate …

Physiology of consumption of human milk oligosaccharides by infant gut-associated bifidobacteria

S Asakuma, E Hatakeyama, T Urashima… - Journal of Biological …, 2011 - ASBMB
The bifidogenic effect of human milk oligosaccharides (HMOs) has long been known, yet the
precise mechanism underlying it remains unresolved. Recent studies show that some …

Nursing our microbiota: molecular linkages between bifidobacteria and milk oligosaccharides

DA Sela, DA Mills - Trends in microbiology, 2010 - cell.com
As the sole nutrition provided to infants, bioactive molecules dissolved in milk influence the
development of our gut microbiota. Accordingly, human milk oligosaccharides (HMOs) are …

Human milk oligosaccharides (HMOS): structure, function, and enzyme-catalyzed synthesis

X Chen - Advances in carbohydrate chemistry and biochemistry, 2015 - Elsevier
The important roles played by human milk oligosaccharides (HMOS), the third major
component of human milk, in the health of breast-fed infants have been increasingly …

Evolutionary adaptation in fucosyllactose uptake systems supports bifidobacteria-infant symbiosis

M Sakanaka, ME Hansen, A Gotoh, T Katoh… - Science …, 2019 - science.org
The human gut microbiota established during infancy has persistent effects on health. In
vitro studies have suggested that human milk oligosaccharides (HMOs) in breast milk …

A novel gene cluster allows preferential utilization of fucosylated milk oligosaccharides in Bifidobacterium longum subsp. longum SC596

D Garrido, S Ruiz-Moyano, N Kirmiz, JC Davis… - Scientific reports, 2016 - nature.com
The infant intestinal microbiota is often colonized by two subspecies of Bifidobacterium
longum: subsp. infantis (B. infantis) and subsp. longum (B. longum). Competitive growth of B …

Cross-feeding by Bifidobacterium breve UCC2003 during co-cultivation with Bifidobacterium bifidum PRL2010 in a mucin-based medium

M Egan, M O'Connell Motherway, M Kilcoyne, M Kane… - BMC microbiology, 2014 - Springer
Background Bifidobacteria constitute a specific group of commensal bacteria that commonly
inhabit the mammalian gastrointestinal tract. Bifidobacterium breve UCC2003 was …

Recent understanding of human milk oligosaccharides in establishing infant gut microbiome and roles in immune system

RP Singh, J Niharika, KK Kondepudi, M Bishnoi… - Food Research …, 2022 - Elsevier
Human milk oligosaccharides (HMOs) are complex sugars with distinctive structural diversity
present in breast milk. HMOs have various functional roles to play in infant development …