The early 2000s brought a new age in the field of mass spectrometry (MS) with the
introduction of ambient ionization MS techniques. As defined by one of its early visionaries …

The possibility of exploiting the analytical power of mass spectrometry to image the
chemistry of biological and similarly complex materials without the use of tags and with good …

The need of cellular and sub‐cellular spatial resolution in laser desorption ionization
(LDI)/matrix‐assisted LDI (MALDI) imaging mass spectrometry (IMS) necessitates micron …

In this review we highlight the general change in perception in the field of ambient mass
spectrometry that it is the immediacy of sample preparation that differentiates the ambient …

The definition of ambient ionization is updated from “no sample preparation” to sample
preparation proximal and in real time with the ionization and analysis step. We differentiate …

Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) is widely used
for characterization of large, thermally labile biomolecules. Advantages of this analytical …

A new inlet ionization method requiring no voltage or laser, and using water, methanol, or
water/organic solvent mixtures, is shown to produce mass spectra similar to those obtained …

While single-cell mass spectrometry can reveal cellular heterogeneity and the molecular
mechanisms of intracellular biochemical reactions, its application is limited by the insufficient …

Virgin olive oil (VOO) is a highly valued vegetable oil often subjected to fraud practices such
as adulteration with lower prized oils such as seed oils and refined olive oil. Thus, there is a …

Mechanistic arguments relative to matrix-assisted laser desorption/ionization (MALDI) mass
spectrometry (MS) address observations that predominately singly charged ions are …