With both catalytic and genetic functions, ribonucleic acid (RNA) is perhaps the most
pluripotent chemical species in molecular biology, and its functions are intimately linked to …

Systematic evolution of ligands by exponential enrichment (SELEX) is a well-established
and efficient technology for the generation of oligonucleotides with a high target affinity …

The protein structure prediction problem has been solved for many types of proteins by
AlphaFold. Recently, there has been considerable excitement to build off the success of …

RNA-binding proteins (RBPs) play important roles in the post-transcriptional control of
RNAs. Identifying RBP binding sites and characterizing RBP binding preferences are key …

Insight into the three-dimensional architecture of RNA is essential for understanding its
cellular functions. However, even the classic transfer RNA structure contains features that …

Non-coding RNAs (ncRNA) are essential for all life, and their functions often depend on their
secondary (2D) and tertiary structure. Despite the abundance of software for the …

The Rfam database, a widely used repository of non-coding RNA families, has undergone
significant updates in release 15.0. This paper introduces major improvements, including the …

Designing a therapeutic modality that will reach a certain organ, tissue, or cell type is crucial
for both the therapeutic efficiency and to limit off-target adverse effects. Nanoparticles …

Prediction categories in the Critical Assessment of Structure Prediction (CASP) experiments
change with the need to address specific problems in structure modeling. In CASP15, four …

Biological functions of RNA molecules are dependent upon sustained specific three-
dimensional (3D) structures of RNA, with or without the help of proteins. Understanding of …