Mesenchymal stem cells: Cell therapy and regeneration potential

C Brown, C McKee, S Bakshi, K Walker… - Journal of tissue …, 2019 - Wiley Online Library
Rapid advances in the isolation of multipotent progenitor cells, routinely called
mesenchymal stromal/stem cells (MSCs), from various human tissues and organs have …

Nanotechnology in cell replacement therapies for type 1 diabetes

AU Ernst, DT Bowers, LH Wang, K Shariati… - Advanced drug delivery …, 2019 - Elsevier
Islet transplantation is a promising long-term, compliance-free, complication-preventing
treatment for type 1 diabetes. However, islet transplantation is currently limited to a narrow …

From mesenchymal stromal/stem cells to insulin-producing cells: progress and challenges

MA Ghoneim, AF Refaie, BL Elbassiouny… - Stem Cell Reviews and …, 2020 - Springer
Mesenchymal stromal cells (MSCs) are an attractive option for cell therapy for type 1
diabetes mellitus (DM). These cells can be obtained from many sources, but bone marrow …

Immune-protective formulations and process strategies for improved survival and function of transplanted islets

Y Shi, YZ Zhao, Z Jiang, Z Wang, Q Wang… - Frontiers in …, 2022 - frontiersin.org
Type 1 diabetes (T1D) is an autoimmune disease caused by the immune system attacking
and destroying insulin-producing β cells in the pancreas. Islet transplantation is becoming …

In vitro generation of transplantable insulin-producing cells from canine adipose-derived mesenchymal stem cells

Q Dang Le, W Rodprasert, S Kuncorojakti… - Scientific reports, 2022 - nature.com
Canine mesenchymal stem cells (cMSCs) have potential applications for regenerative
therapy, including the generation of insulin-producing cells (IPCs) for studying and treating …

A porcine islet-encapsulation device that enables long-term discordant xenotransplantation in immunocompetent diabetic mice

K Ajima, N Tsuda, T Takaki, S Furusako… - Cell Reports …, 2023 - cell.com
Islet transplantation is an effective treatment for type 1 diabetes (T1D). However, a shortage
of donors and the need for immunosuppressants are major issues. The ideal solution is to …

Inducible pluripotent stem cells as a potential cure for diabetes

K Verhoeff, SJ Henschke, BA Marfil-Garza… - Cells, 2021 - mdpi.com
Over the last century, diabetes has been treated with subcutaneous insulin, a discovery that
enabled patients to forego death from hyperglycemia. Despite novel insulin formulations …

Mesenchymal stem cells: an excellent candidate for the treatment of diabetes mellitus

Q Huang, Y Huang, J Liu - International Journal of …, 2021 - Wiley Online Library
Mesenchymal stem cells (MSCs) are adult stem cells (ASCs) known for repairing damaged
cells, exerting anti‐inflammatory responses and producing immunoregulatory effects that …

Mesenchymal stem cell-based therapy for diabetes mellitus: enhancement strategies and future perspectives

H Li, H Zhu, T Ge, Z Wang, C Zhang - Stem cell reviews and reports, 2021 - Springer
Diabetes mellitus (DM), a chronic disorder of carbohydrate metabolism, is characterized by
the unbridled hyperglycemia resulted from the impaired ability of the body to either produce …

Effect and mechanism of human umbilical cord mesenchymal stem cells in treating allergic rhinitis in mice

X Kan, X Pan, J Zhao, J He, X Cai, R Pang, X Zhu… - Scientific reports, 2020 - nature.com
A model of allergic rhinitis (AR) in BALB/c mice was established and evaluated to provide
experimental subjects for further research. Preparation of human umbilical cord …