[HTML][HTML] Mechanisms of SARS-CoV-2 entry into cells

CB Jackson, M Farzan, B Chen, H Choe - Nature reviews Molecular …, 2022 - nature.com
The unprecedented public health and economic impact of the COVID-19 pandemic caused
by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been …

[HTML][HTML] The germinal centre B cell response to SARS-CoV-2

BJ Laidlaw, AH Ellebedy - Nature Reviews Immunology, 2022 - nature.com
The germinal centre (GC) response is critical for the generation of affinity-matured plasma
cells and memory B cells capable of mediating long-term protective immunity …

[HTML][HTML] Germinal centre-driven maturation of B cell response to mRNA vaccination

W Kim, JQ Zhou, SC Horvath, AJ Schmitz, AJ Sturtz… - Nature, 2022 - nature.com
Germinal centres (GC) are lymphoid structures in which B cells acquire affinity-enhancing
somatic hypermutations (SHM), with surviving clones differentiating into memory B cells …

Membrane fusion and immune evasion by the spike protein of SARS-CoV-2 Delta variant

J Zhang, T Xiao, Y Cai, CL Lavine, H Peng, H Zhu… - Science, 2021 - science.org
The Delta variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
outcompeted previously prevalent variants and become a dominant strain worldwide. We …

[HTML][HTML] Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants

K Wang, Z Jia, L Bao, L Wang, L Cao, H Chi, Y Hu, Q Li… - Nature, 2022 - nature.com
Abstract Omicron (B. 1.1. 529), the most heavily mutated SARS-CoV-2 variant so far, is
highly resistant to neutralizing antibodies, raising concerns about the effectiveness of …

[HTML][HTML] Mutations in SARS-CoV-2 variants of concern link to increased spike cleavage and virus transmission

A Escalera, AS Gonzalez-Reiche, S Aslam, I Mena… - Cell host & …, 2022 - cell.com
SARS-CoV-2 lineages have diverged into highly prevalent variants termed" variants of
concern"(VOCs). Here, we characterized emerging SARS-CoV-2 spike polymorphisms in …

Antibody-mediated neutralization of SARS-CoV-2

H Gruell, K Vanshylla, T Weber, CO Barnes, C Kreer… - Immunity, 2022 - cell.com
Neutralizing antibodies can block infection, clear pathogens, and are essential to provide
long-term immunity. Since the onset of the pandemic, SARS-CoV-2 neutralizing antibodies …

Structure of SARS-CoV-2 spike protein

J Zhang, T Xiao, Y Cai, B Chen - Current opinion in virology, 2021 - Elsevier
The COVID-19 (coronavirus disease 2019) pandemic, caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has led to loss of human life in millions and …

[HTML][HTML] Large-scale study of antibody titer decay following BNT162b2 mRNA vaccine or SARS-CoV-2 infection

A Israel, Y Shenhar, I Green, E Merzon, A Golan-Cohen… - Vaccines, 2021 - mdpi.com
Immune protection following either vaccination or infection with SARS-CoV-2 is thought to
decrease over time. We designed a retrospective study, conducted at Leumit Health …

Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants

Y Cai, J Zhang, T Xiao, CL Lavine, S Rawson, H Peng… - Science, 2021 - science.org
Several fast-spreading variants of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) have become the dominant circulating strains in the COVID-19 pandemic. We report …