Aortic aneurysm is a cardiovascular disease related to the alteration of the aortic tissue. It is
an important cause of death in developed countries, especially for older patients. The …

Thoracic aortic aneurysm (TAA) is a focal enlargement of the thoracic aorta, but the etiology
of this disease is not fully understood. Previous work suggests that various genetic …

Computational hemodynamics has become increasingly important within the context of
precision medicine, providing major insight in cardiovascular pathologies. However, finding …

The medical digital twin is emerging as a viable opportunity to provide patient-specific
information useful for treatment, prevention and surgical planning. A bottleneck toward its …

Purpose Computational fluid dynamics (CFD) and 4D-flow magnetic resonance imaging
(MRI) are synergically used for the simulation and the analysis of the flow in a patient …

Transcatheter aortic valve implantation (TAVI) is a minimally invasive intervention for the
treatment of severe aortic valve stenosis. The main cause of failure is the structural …

Numerical simulations to evaluate thoracic aortic hemodynamics include a computational
fluid dynamic (CFD) approach or fluid-structure interaction (FSI) approach. While CFD …

In the context of aortic hemodynamics, uncertainties affecting blood flow simulations hamper
their translational potential as supportive technology in clinics. Computational fluid dynamics …

Statistical Shape Models (SSMs) are well-established tools for assessing the variability of
3D geometry and for broadening a limited set of shapes. They are widely used in medical …

The Modified Blalock Taussig Shunt (MBTS) is one of the most common palliative operations
in case of cyanotic heart diseases. Thus far, the decision on the position, size, and geometry …