[HTML][HTML] Serratiopeptidase: Insights into the therapeutic applications

SB Jadhav, N Shah, A Rathi, V Rathi, A Rathi - Biotechnology Reports, 2020 - Elsevier
Therapeutic applications of enzymes have been widely accepted in clinical practices for
decades. Proteolytic enzymes in particular, have been used for the treatment of diseases …

Microbial fibrinolytic enzymes as anti-thrombotics: production, characterisation and prodigious biopharmaceutical applications

C Sharma, A Osmolovskiy, R Singh - Pharmaceutics, 2021 - mdpi.com
Cardiac disorders such as acute myocardial infarction, embolism and stroke are primarily
attributed to excessive fibrin accumulation in the blood vessels, usually consequential in …

[HTML][HTML] The role of serratiopeptidase in the resolution of inflammation

M Tiwari - Asian journal of pharmaceutical sciences, 2017 - Elsevier
Inflammation remains a key event during most of the diseases and physiological imbalance.
Acute inflammation is an essential physiological event by immune system for a protective …

[HTML][HTML] Serratiopeptidase: a systematic review of the existing evidence

S Bhagat, M Agarwal, V Roy - International Journal of Surgery, 2013 - Elsevier
BACKGROUND: Serratiopeptidase is a proteolytic enzyme prescribed in various specialities
like surgery, orthopaedics, otorhinolaryngology, gynaecology and dentistry for its anti …

Effect of the proteolytic enzyme serrapeptase on swelling, pain and trismus after surgical extraction of mandibular third molars

TH Al-Khateeb, Y Nusair - International journal of oral and maxillofacial …, 2008 - Elsevier
The aim of this study was to investigate the ability of serrapeptase to reduce postoperative
swelling, pain and trismus after third molar surgery. Twenty-four healthy individuals with …

Serrapeptase and nattokinase intervention for relieving Alzheimer's disease pathophysiology in rat model

NN Fadl, HH Ahmed, HF Booles… - Human & experimental …, 2013 - journals.sagepub.com
Serrapeptase (SP) and nattokinase (NK) are proteolytic enzymes belonging to serine
proteases. In this study, we hypothesized that SP and NK could modulate certain factors that …

Improved anti-biofilm activity and long-lasting effects of novel serratiopeptidase immobilized on cellulose nanofibers

M Rouhani, V Valizadeh, H Bakhshandeh… - Applied Microbiology …, 2023 - Springer
Today, enzymatic treatment is a progressive field in combating biofilm producing pathogens.
In this regard, serratiopeptidase, a medicinally important metalloprotease, has been recently …

Preparation, characterization and targeted delivery of serratiopeptidase immobilized on amino-functionalized magnetic nanoparticles

S Kumar, AK Jana, I Dhamija, Y Singla… - European Journal of …, 2013 - Elsevier
Targeted delivery of serratiopeptidase enzyme immobilized on magnetic nanoparticles
(MNPs) of Fe 3 O 4 has been reported for the treatment using this enzyme. The enzyme was …

Applications of microbial proteases in pharmaceutical industry: an overview

P Chanalia, D Gandhi, D Jodha… - Reviews and Research in …, 2011 - journals.lww.com
Proteases are ubiquitous to all the living organisms. Their involvement in the life cycle of
various disease causing organisms has led them to become a potential target for developing …

The effect of proteolytic enzyme serratiopeptidase in the treatment of experimental implant-related infection

M Mecikoglu, B Saygi, Y Yildirim, E Karadag-Saygi… - JBJS, 2006 - journals.lww.com
Background: Infection around an implanted orthopaedic device is a devastating
complication, and the treatment of infections involving slime-forming bacteria is especially …