Cellular membranes are formed from a chemically diverse set of lipids present in various
amounts and proportions. A high lipid diversity is universal in eukaryotes and is seen from …

The diversity of glycerophospholipid species in cellular membranes is immense and affects
various biological functions. Glycerol-3-phosphate acyltransferases (GPATs) and …

Phosphatidic acid (PA) is the simplest cellular glycerophospholipid characterized by unique
biophysical properties: a small headgroup; negative charge; and a phosphomonoester …

The past few decades have seen emerging growth in the field of soft materials for synthetic
biology. This review focuses on soft materials involved in biological and artificial …

In eukaryotic cells, protein sorting is a highly regulated mechanism important for many
physiological events. After synthesis in the endoplasmic reticulum and trafficking to the Golgi …

Double membrane vesicles (DMVs) serve as replication organelles of plus-strand RNA
viruses such as hepatitis C virus (HCV) and SARS-CoV-2. Viral DMVs are morphologically …

Lipids function not only as the major structural components of cell membranes, but also as
molecular messengers that transduce signals to trigger downstream signaling events in the …

Membrane lipidomes are dynamic and their changes generate lipid mediators affecting
various biological processes. Phosphatidic acid (PA) has emerged as an important class of …

Abstract Phosphatidylinositol 4-phosphate (PI4P) is a membrane glycerophospholipid and a
major regulator of the characteristic appearance of the Golgi complex as well as its vesicular …

The C-terminal variants G1 and G2 of apolipoprotein L1 (APOL1) confer human resistance
to the sleeping sickness parasite Trypanosoma rhodesiense, but they also increase the risk …