The aldol addition is one of the most important methods for stereoselective construction of
carboncarbon bonds. New and powerful variants of these classical reactions have been …

The aldol reaction is one of the most important methods for the stereoselective construction
of polyketide natural products, not only for nature but also for synthetic chemistry. The …

Gathering together the widespread literature in the field, this monograph acts as a reference
guide to this very important chemical reaction. Following an introduction, the book goes on …

Erythromycin and rapamycin are both macrolide antibiotics. 1, 2 Erythromycin A (1) belongs
to a large family of macrolides which are characterized by rings containing 12, 14, or 16 …

Use of abundant feedstock pronucleophiles in catalytic carbonyl reductive coupling
enhances efficiency in target‐oriented synthesis. For such reactions, equally inexpensive …

The development and application of stereoselective and site-selective catalytic methods that
directly convert lower alcohols to higher alcohols are described. These processes merge the …

Covering: up to the end of 2013 Despite the longstanding importance of polyketide natural
products in human medicine, nearly all commercial polyketide-based drugs are prepared …

The selective formation of bondings between molecules is one of the major challenges in
organic chemistry, and the so-called aldol reaction is one of the most important for this …

Natural products (or secondary metabolites) remain as the most important source for
discovery of new and potential drug molecules. With high resolution data of their structures …

The asymmetric syntheses of 6-deoxyerythronolide B (1) and oleandolide (2) have been
achieved, each in 18 linear steps. These syntheses demonstrate the utility of chiral β-keto …