Butterfly Pea (Clitoria ternatea), a Cyclotide-Bearing Plant With Applications in Agriculture and Medicine

GK Oguis, EK Gilding, MA Jackson… - Frontiers in plant …, 2019 - frontiersin.org
The perennial leguminous herb Clitoria ternatea (butterfly pea) has attracted significant
interest based on its agricultural and medical applications, which range from use as a fodder …

Cyclotides: from structure to function

SJ De Veer, MW Kan, DJ Craik - Chemical reviews, 2019 - ACS Publications
This Review explores the class of plant-derived macrocyclic peptides called cyclotides. We
include an account of their discovery, characterization, and distribution in the plant kingdom …

[HTML][HTML] Comparative study on molecular and higher-order structures of legume seed protein isolates: Lentil, mungbean and yellow pea

S Shrestha, L van't Hag, V Haritos, S Dhital - Food Chemistry, 2023 - Elsevier
Lentils and mungbean proteins are under-researched compared to pea and soybean.
Lentils (green, red and black-lentils), mungbean and yellow pea protein isolates were …

Biosynthesis, bioactivity, biotoxicity and applications of antimicrobial peptides for human health

D Wei, X Zhang - Biosafety and Health, 2022 - mednexus.org
Antimicrobial peptides (AMPs) are the natural antibiotics recognized for their broad-
spectrum resistance to bacteria, fungi, viruses and parasites, and influencing the host …

Anionic antimicrobial peptides from eukaryotic organisms

F Harris, SR Dennison… - Current Protein and …, 2009 - ingentaconnect.com
Anionic antimicrobial peptides/proteins (AAMPs) were first reported in the early 1980s and
since then, have been established as an important part of the innate immune systems of …

Cysteine‐rich antimicrobial peptides from plants: The future of antimicrobial therapy

S Srivastava, K Dashora, KL Ameta… - Phytotherapy …, 2021 - Wiley Online Library
There has been a spurt in the spread of microbial resistance to antibiotics due to
indiscriminate use of antimicrobial agents in human medicine, agriculture, and animal …

The cyclotide cycloviolacin O2 from Viola odorata has potent bactericidal activity against Gram-negative bacteria

M Pränting, C Lööv, R Burman… - Journal of …, 2010 - academic.oup.com
Objectives To determine the antibacterial activity of small cyclic plant proteins, ie cyclotides,
and the importance of the surface exposed charged residues for activity. Methods Prototypic …

Distribution and evolution of circular miniproteins in flowering plants

CW Gruber, AG Elliott, DC Ireland, PG Delprete… - The Plant …, 2008 - academic.oup.com
Cyclotides are disulfide-rich miniproteins with the unique structural features of a circular
backbone and knotted arrangement of three conserved disulfide bonds. Cyclotides have …

Identification and characterization of a new family of cell-penetrating peptides: cyclic cell-penetrating peptides

L Cascales, ST Henriques, MC Kerr, YH Huang… - Journal of Biological …, 2011 - ASBMB
Cell-penetrating peptides can translocate across the plasma membrane of living cells and
thus are potentially useful agents in drug delivery applications. Disulfide-rich cyclic peptides …

Discovery and characterization of novel cyclotides originated from chimeric precursors consisting of albumin-1 chain a and cyclotide domains in the Fabaceae family

GKT Nguyen, S Zhang, NTK Nguyen… - Journal of Biological …, 2011 - ASBMB
The tropical plant Clitoria ternatea is a member of the Fabaceae family well known for its
medicinal values. Heat extraction of C. ternatea revealed that the bioactive fractions …