Abstract The Ca2+-sensing receptor (CaSR) is a dimeric family CG protein-coupled receptor
that is expressed in calcitropic tissues such as the parathyroid glands and the kidneys and …

Recent studies have revealed biologically significant differences between human and
mouse lung development, and have reported new in vitro systems that allow experimental …

Coronaviruses (CoVs) are a major infectious disease threat and include the pathogenic
human pathogens of zoonotic origin: severe acute respiratory syndrome CoV (SARS-CoV) …

Coronaviruses are a major infectious disease threat, and include the zoonotic-origin human
pathogens SARS-CoV-2, SARS-CoV, and MERS-CoV (SARS-2, SARS-1, and MERS). Entry …

Airway structure and function are key aspects of normal lung development, growth, and
aging, as well as of lung responses to the environment and the pathophysiology of important …

Iodide (I−) metabolism is crucial for the synthesis of thyroid hormones (THs) in the thyroid
and the subsequent action of these hormones in the organism. I− is principally transported …

Maintenance of normal epithelial ion and water transport in the lungs includes providing a
thin layer of surface liquid that coats the conducting airways. This airway surface liquid is …

Rationale: Lung disease is the major cause of morbidity and mortality in persons with cystic
fibrosis (pwCF). Variability in CF lung disease has substantial non-CFTR (CF …

The tear-producing lacrimal gland is a tubular organ that protects and lubricates the ocular
surface. The lacrimal gland possesses many features that make it an excellent model in …

The Ca2+-sensing receptor (CaSR) is a class-C G protein-coupled receptor which plays a
pivotal role in calciotropic processes, primarily in regulating parathyroid hormone secretion …