Methylene blue (MB) is a well-established drug with a long history of use, owing to its
diverse range of use and its minimal side effect profile. MB has been used classically for the …

Trazodone is an antidepressant that is FDA-approved for the treatment of depression. It has
been used by mental health and primary care providers for the treatment of multiple …

Serotonin syndrome is thought to arise from serotonin excess. In many cases, symptoms are
mild and self-limiting. But serotonin syndrome can become life threatening, when …

Purpose As the general population lives longer, the perioperative physician is more likely to
encounter disease states that increase in incidence in an aging population. This review …

Background Serotonin syndrome (SS) is a potentially serious side effect of serotonergic
drugs. Cases of SS have been reported from the administration of methylene blue (MB), an …

Objectives Methylene blue commonly is used as a dye or an antidote, but also can be used
off label as a vasopressor. Serotonin toxicity is a potentially lethal and often misdiagnosed …

Introduction Management of severe vasoplegic shock in overdose can be very challenging.
We describe a case of severe refractory vasodilatory shock in poisoning where methylene …

DISCUSSION The Hunter criteria suggest serotonin toxicity in the presence of a serotonergic
agent—paroxetine and quetiapine in this patient—and 1 of the 5 following clusters of …

Objective: Unusual clinical course Background: Serotonin syndrome (SS) involves
serotonergic hyperactivity caused by excessive activation of 5-HT2A receptors. As the use of …

Discussion This article presents the first case of serotonin syndrome after a routine LVAD
implantation and is the fourteenth case of serotonin syndrome in cardiology literature (Video …