Metabolomics-centered mining of plant metabolic diversity and function: Past decade and future perspectives
S Shen, C Zhan, C Yang, AR Fernie, J Luo - Molecular Plant, 2023 - cell.com
Plants are natural experts in organic synthesis, being able to generate large numbers of
specific metabolites with widely varying structures that help them adapt to variable survival …
specific metabolites with widely varying structures that help them adapt to variable survival …
Guide to metabolomics analysis: a bioinformatics workflow
Y Chen, EM Li, LY Xu - Metabolites, 2022 - mdpi.com
Metabolomics is an emerging field that quantifies numerous metabolites systematically. The
key purpose of metabolomics is to identify the metabolites corresponding to each biological …
key purpose of metabolomics is to identify the metabolites corresponding to each biological …
Microbiome-derived inosine modulates response to checkpoint inhibitor immunotherapy
Several species of intestinal bacteria have been associated with enhanced efficacy of
checkpoint blockade immunotherapy, but the underlying mechanisms by which the …
checkpoint blockade immunotherapy, but the underlying mechanisms by which the …
The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine
Low-protein diets promote metabolic health in rodents and humans, and the benefits of low-
protein diets are recapitulated by specifically reducing dietary levels of the three branched …
protein diets are recapitulated by specifically reducing dietary levels of the three branched …
Supplementation with a probiotic mixture accelerates gut microbiome maturation and reduces intestinal inflammation in extremely preterm infants
J Samara, S Moossavi, B Alshaikh, VA Ortega… - Cell host & …, 2022 - cell.com
Probiotics are increasingly administered to premature infants to prevent necrotizing
enterocolitis and neonatal sepsis. However, their effects on gut microbiome assembly and …
enterocolitis and neonatal sepsis. However, their effects on gut microbiome assembly and …
Fasting drives the metabolic, molecular and geroprotective effects of a calorie-restricted diet in mice
Calorie restriction (CR) promotes healthy ageing in diverse species. Recently, it has been
shown that fasting for a portion of each day has metabolic benefits and promotes lifespan …
shown that fasting for a portion of each day has metabolic benefits and promotes lifespan …
Conversion of Escherichia coli to generate all biomass carbon from CO2
The living world is largely divided into autotrophs that convert CO 2 into biomass and
heterotrophs that consume organic compounds. In spite of widespread interest in renewable …
heterotrophs that consume organic compounds. In spite of widespread interest in renewable …
Tumour-associated macrophages drive stromal cell-dependent collagen crosslinking and stiffening to promote breast cancer aggression
Stromal stiffening accompanies malignancy, compromises treatment and promotes tumour
aggression. Clarifying the molecular nature and the factors that regulate stromal stiffening in …
aggression. Clarifying the molecular nature and the factors that regulate stromal stiffening in …
[HTML][HTML] Signatures of mitochondrial dysfunction and impaired fatty acid metabolism in plasma of patients with post-acute sequelae of COVID-19 (PASC)
Exercise intolerance is a major manifestation of post-acute sequelae of severe acute
respiratory syndrome coronavirus infection (PASC, or “long-COVID”). Exercise intolerance in …
respiratory syndrome coronavirus infection (PASC, or “long-COVID”). Exercise intolerance in …
[HTML][HTML] p53 represses the mevalonate pathway to mediate tumor suppression
There are still gaps in our understanding of the complex processes by which p53
suppresses tumorigenesis. Here we describe a novel role for p53 in suppressing the …
suppresses tumorigenesis. Here we describe a novel role for p53 in suppressing the …