It has been 20 years since Brachypodium distachyon was suggested as a model grass
species, but ongoing research now encompasses the entire genus. Extensive …

INTRODUCTION Genomes are spatially organized across length scales from single base
pairs to whole chromosomes. This organization is thought to regulate gene expression and …

Recent studies in yeast reveal an intricate interplay between nuclear envelope (NE)
architecture and lipid metabolism, and between lipid signaling and both epigenome and …

Studying the similarities and differences in genomic interactions between species provides
fertile grounds for determining the evolutionary dynamics underpinning genome function …

Genome compaction and activity in the nucleus depend on spatiotemporal changes in the
organization of chromatins in chromosomes. However, the direct imaging of the …

Closing each strand of a DNA duplex upon itself fixes its linking number L. This topological
condition couples together the secondary and tertiary structures of the resulting ccDNA …

Patterns of genomic architecture across insects remain largely undocumented or decoupled
from a broader phylogenetic context. For instance, it is unknown whether translocation rates …

The evolution of eukaryotic genomes is accompanied by fluctuations in chromosome
number, reflecting cycles of chromosome number increase (polyploidy and centric fissions) …

Yeast artificial chromosomes (YACs) are important tools for sequencing, gene cloning, and
transferring large quantities of genetic information. However, the structure and activity of …

Non-homologous chromosomal contacts (NHCCs) between different chromosomes
participate considerably in gene and genome regulation. Due to analytical challenges …