Gangliosides are glycosphingolipids highly abundant in the nervous system, and carry most
of the sialic acid residues in the brain. Gangliosides are enriched in cell membrane …

Membrane rafts are dynamic, small (10–200 nm) domains enriched with cholesterol and
sphingolipids that compartmentalize cellular processes. Rafts participate in roles essential to …

The human mechanosensitive ion channel PIEZO1 is gated by membrane tension and
regulates essential biological processes such as vascular development and erythrocyte …

An evolutionarily conserved feature of cellular organelles is the distinct phospholipid
composition of their bounding membranes, which is essential to their identity and function …

Hepatitis B virus (HBV) is a leading cause of cirrhosis and hepatocellular carcinoma
worldwide, with 250 million individuals chronically infected. Many stages of the HBV …

Platelets protect the vascular system during damage or inflammation, but platelet activation
can result in pathological thrombosis. Activated platelets release a variety of extracellular …

AB5 bacterial toxins and polyomaviruses induce membrane curvature as a mechanism to
facilitate their entry into host cells. How membrane bending is accomplished is not yet fully …

Cholera toxin B-subunit (CTxB) has emerged as one of the most widely utilized tools in
membrane biology and biophysics. CTxB is a homopentameric stable protein that binds …

GM1 is one of the major glycosphingolipids (GSLs) on the cell surface in the central nervous
system (CNS). Its expression level, distribution pattern, and lipid composition are dependent …

Trichomonas vaginalis, a human-infective parasite, causes the most prevalent nonviral
sexually transmitted infection worldwide. This pathogen secretes extracellular vesicles (EVs) …