MicroRNAs in neuroinflammation: implications in disease pathogenesis, biomarker discovery and therapeutic applications

JA Slota, SA Booth - Non-coding RNA, 2019 - mdpi.com
The central nervous system can respond to threat via the induction of an inflammatory
response. Under normal circumstances this response is tightly controlled, however …

MicroRNAs in infectious diseases: potential diagnostic biomarkers and therapeutic targets

M Kimura, S Kothari, W Gohir… - Clinical microbiology …, 2023 - Am Soc Microbiol
MicroRNAs (miRNAs) are conserved, short, non-coding RNAs that play a crucial role in the
post-transcriptional regulation of gene expression. They have been implicated in the …

Herpesviruses: harmonious pathogens but relevant cofactors in other diseases?

S Sehrawat, D Kumar, BT Rouse - Frontiers in cellular and infection …, 2018 - frontiersin.org
Most vertebrates are infected with one or more herpesviruses and remain so for the rest of
their lives. The relationship of immunocompetent healthy host with herpesviruses may …

The role of microRNAs in the pathogenesis of herpesvirus infection

D Piedade, JM Azevedo-Pereira - Viruses, 2016 - mdpi.com
MicroRNAs (miRNAs) are small non-coding RNAs important in gene regulation. They are
able to regulate mRNA translation through base-pair complementarity. Cellular miRNAs …

Cell death pathways and viruses: role of microRNAs

JS Nahand, L Shojaie, SA Akhlagh… - … Therapy-Nucleic Acids, 2021 - cell.com
Viral infections lead to the death of more than a million people each year around the world,
both directly and indirectly. Viruses interfere with many cell functions, particularly critical …

Circular RNA circDtx1 regulates IRF3-mediated antiviral immune responses through suppression of miR-15a-5p-dependent TRIF downregulation in teleost fish

W Zheng, Q Chu, L Yang, L Sun, T Xu - PLoS pathogens, 2021 - journals.plos.org
Circular RNAs (circRNAs) represent a class of widespread and diverse covalently closed
circular endogenous RNAs that exert crucial functions in regulating gene expression in …

The diverse roles of microRNAs at the host–virus interface

A Bernier, SM Sagan - Viruses, 2018 - mdpi.com
MicroRNAs (miRNAs) are small, non-coding RNAs that regulate gene expression at the post-
transcriptional level. Through this activity, they are implicated in almost every cellular …

The role of miR‐146a in viral infection

JS Nahand, MR Karimzadeh, M Nezamnia… - IUBMB …, 2020 - Wiley Online Library
Cellular microRNAs (miRNAs) were identified as a key player in the posttranscriptional
regulation of cellular‐genes regulatory pathways. They also emerged as a significant …

A comprehensive overview on the crosstalk between microRNAs and viral pathogenesis and infection

SZ Bahojb Mahdavi, A Jebelli… - Medicinal research …, 2024 - Wiley Online Library
Infections caused by viruses as the smallest infectious agents, pose a major threat to global
public health. Viral infections utilize different host mechanisms to facilitate their own …

HSV-1-induced disruption of transcription termination resembles a cellular stress response but selectively increases chromatin accessibility downstream of genes

T Hennig, M Michalski, AJ Rutkowski, L Djakovic… - PLoS …, 2018 - journals.plos.org
Lytic herpes simplex virus 1 (HSV-1) infection triggers disruption of transcription termination
(DoTT) of most cellular genes, resulting in extensive intergenic transcription. Similarly …