Guideline for the management of myasthenic syndromes

H Wiendl, A Abicht, A Chan… - Therapeutic …, 2023 - journals.sagepub.com
Myasthenia gravis (MG), Lambert-Eaton myasthenic syndrome (LEMS), and congenital
myasthenic syndromes (CMS) represent an etiologically heterogeneous group of (very) rare …

Novel pathophysiological insights in autoimmune myasthenia gravis

G Masi, KC O'Connor - Current opinion in neurology, 2022 - journals.lww.com
Recent advances in the understanding of autoantibody functionalities are bringing
neuroimmunologists closer to a more detailed appreciation of the mechanisms that govern …

Rituximab treatment in myasthenia gravis

A Vesperinas-Castro, E Cortés-Vicente - Frontiers in Neurology, 2023 - frontiersin.org
Myasthenia gravis (MG) is a chronic autoimmune disease mediated by antibodies against
post-synaptic proteins of the neuromuscular junction. Up to 10%–30% of patients are …

Conventional and emerging treatments and controversies in myasthenia gravis

A Evoli, V Damato - Expert Review of Neurotherapeutics, 2023 - Taylor & Francis
Introduction Myasthenia gravis (MG) is caused by IgG antibodies against different proteins at
the neuromuscular junction. Anti-acetylcholine receptor (AChR) Abs are detected in the …

Application of lymphoplasmapheresis in the treatment of severe myasthenia gravis

W Duan, H Zhou, X Dong, B Li, Y Li, H Cai… - Frontiers in …, 2022 - frontiersin.org
Background Lymphoplasmapheresis (LPE) is a treatment that combines traditional plasma
exchange and lymphocyte removal technique. It has been applied to treat a variety of …

Current state and perspectives of CAR T cell therapy in central nervous system diseases

LK Pfeffer, F Fischbach, C Heesen, MA Friese - Brain, 2024 - academic.oup.com
Abstract B cell-directed CAR T cell therapy has fundamentally changed the treatment of
hematological malignancies and its scope of application is rapidly expanding to include …

For a dementia diagnosis, clinical acumen must precede biomarkers

DS Knopman - The Lancet Neurology, 2024 - thelancet.com
Cognitive impairment in later life can be caused by one or more neurodegenerative
diseases or by cerebrovascular disease, in various combinations. Fluid and imaging …

Refractory myasthenia gravis treated with autologous hematopoietic stem cell transplantation

B Beland, J Storek, L Quartermain… - Annals of Clinical …, 2024 - Wiley Online Library
Objectives Patients with refractory myasthenia gravis (MG) have few treatment options.
Autologous hematopoietic stem cell transplantation (HSCT) has been used to treat immune …

Therapeutic challenges and unmet needs in the management of myasthenia gravis: an Italian expert opinion

R Mantegazza, F Saccà, G Antonini, DM Bonifati… - Neurological …, 2024 - Springer
Myasthenia gravis (MG) is a rare, autoimmune, neurological disorder. Most MG patients
have autoantibodies against acetylcholine receptors (AChRs). Some have autoantibodies …

Advancements and prospects of novel biologicals for myasthenia gravis: toward personalized treatment based on autoantibody specificities

C Ma, D Liu, B Wang, Y Yang, R Zhu - Frontiers in Pharmacology, 2024 - frontiersin.org
Myasthenia gravis (MG) is an antibody-mediated autoimmune disease with a prevalence of
150–250 cases per million individuals. Autoantibodies include long-lived antibodies against …