Biomarkers for Pre-Treatment Risk Stratification of Prostate Cancer Patients: A Systematic Review

JP Sequeira, S Salta, R Freitas, R López-López… - Cancers, 2024 - mdpi.com
Simple Summary PCa remains a leading health concern worldwide. Serum PSA-based PCa
screening led to a well-documented decreased mortality but at the cost of the increased …

Prostate cancer epigenetics—from pathophysiology to clinical application

V Constâncio, J Lobo, JP Sequeira, R Henrique… - Nature Reviews …, 2025 - nature.com
Prostate cancer is a multifactorial disease influenced by various molecular features. Over the
past decades, epigenetics, which is the study of changes in gene expression without altering …

[HTML][HTML] High Sensitivity and Specificity Platform to Validate MicroRNA Biomarkers in Cancer and Human Diseases

A Kanavarioti, MH Rehman, S Qureshi, A Rafiq… - Non-coding RNA, 2024 - mdpi.com
We developed a technology for detecting and quantifying trace nucleic acids using a
bracketing protocol designed to yield a copy number with approximately±20% accuracy …

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Y Hayashi, JC Millen, RI Ramos, JA Linehan… - Molecular …, 2024 - Wiley Online Library
As cutting‐edge technologies applied for the study of body fluid molecular biomarkers are
continuously evolving, clinical applications of these biomarkers improve. Diverse forms of …

Circulating miR-1-3p, miR-96-5p, miR-148a-3p, and miR-375-3p support differentiation between prostate cancer and benign prostate lesions

R Osiecki, P Popławski, D Sys, J Bogusławska… - Clinical Genitourinary …, 2024 - Elsevier
Introduction microRNAs (miRNAs) are small non-coding RNAs and promising cancer
biomarkers. Prostate-specific antigen (PSA) testing revolutionized prostate cancer (PCa) …

Analytical platform to validate microRNA biomarkers for cancer or disease with practically 100% sensitivity and specificity

A Kanavarioti, MH Rehman, S Qureshi, A Rafiq… - medRxiv, 2024 - medrxiv.org
We developed a technology for detecting and quantifying trace nucleic acids using a
bracketing protocol designed to yield a copy number with approximately±20% accuracy …