Synthesis and reactivity of propargylamines in organic chemistry

K Lauder, A Toscani, N Scalacci… - Chemical reviews, 2017 - ACS Publications
Propargylamines are a versatile class of compounds which find broad application in many
fields of chemistry. This review aims to describe the different strategies developed so far for …

Sustainable metal catalysis in CH activation

NV Tzouras, IK Stamatopoulos, AT Papastavrou… - Coordination Chemistry …, 2017 - Elsevier
The omnipresence of Csingle bondH bonds in organic compounds renders them highly
attractive targets for the installation of functional groups towards the construction of valuable …

Cadmium‐Doped and Pincer Ligand‐Modified Gold Nanocluster for Catalytic KA2 Reaction

JQ Fan, Y Yang, CB Tao, MB Li - Angewandte Chemie, 2023 - Wiley Online Library
A gold nanocluster Au17Cd2 (PNP) 2 (SR) 12 (PNP= 2, 6‐bis (diphenylphosphinomethyl)
pyridine, SR= 4‐MeOPhS) consisting of an icosahedral Au13 kernel, two Au2CdS6 staple …

Synthesis, characterization, catalytic activity, and DFT calculations of Zn (II) hydrazone complexes

TT Adejumo, NV Tzouras, LP Zorba, D Radanović… - Molecules, 2020 - mdpi.com
Two new Zn (II) complexes with tridentate hydrazone-based ligands (condensation products
of 2-acetylthiazole) were synthesized and characterized by infrared (IR) and nuclear …

Metal-free multicomponent approach for the synthesis of propargylamine: A review

S Ghosh, K Biswas - RSC advances, 2021 - pubs.rsc.org
Propargylamines are important classes of alkyne coupled amine compounds used in
heterocyclic chemistry and pharmaceuticals chemistry and have a large impact as a …

The Ketone-Amine-Alkyne (KA2) coupling reaction: Transition metal-catalyzed synthesis of quaternary propargylamines

LP Zorba, GC Vougioukalakis - Coordination Chemistry Reviews, 2021 - Elsevier
Abstract “Green chemistry” and sustainable catalysis are increasingly attracting significant
attention, in both industry and academia. Multicomponent reactions aim towards “greener” …

Zn-Catalyzed Multicomponent KA2 Coupling: One-Pot Assembly of Propargylamines Bearing Tetrasubstituted Carbon Centers

NV Tzouras, SP Neofotistos, GC Vougioukalakis - ACS omega, 2019 - ACS Publications
Tetrasubstituted propargylamines comprise a unique class of highly useful compounds,
which can be accessed through the multicomponent coupling between ketones, amines …

α-Tertiary Propargylamine Synthesis via KA2-Type Coupling Reactions under Solvent-Free CuI-Zeolite Catalysis

F Schlimpen, C Plaçais, E Starck… - The Journal of …, 2021 - ACS Publications
The potential of copper (I)-zeolite catalysis was evaluated in the three-component KA2-
coupling mediated synthesis of α-tertiary propargylamines. Our archetypal copper (I)-doped …

Manganese‐Catalyzed Multicomponent Synthesis of Tetrasubstituted Propargylamines: System Development and Theoretical Study

SP Neofotistos, NV Tzouras, M Pauze… - Advanced Synthesis …, 2020 - Wiley Online Library
Herein, we report a catalytic system based on the earth‐abundant manganese for the
ketone, amine, alkyne (KA2) reaction. The efficiency of manganese manifests at relatively …

Making copper (0) nanoparticles in glycerol: a straightforward synthesis for a multipurpose catalyst

T Dang‐Bao, C Pradel, I Favier… - Advanced Synthesis & …, 2017 - Wiley Online Library
Small zero‐valent copper nanoparticles (CuNPs) have been straightforwardly prepared from
Cu (I) and Cu (II) precursors in glycerol and in the presence of polyvinylpyrrolidone as …