Computational prediction of the behavior of concentrated protein solutions is particularly
advantageous in early development stages of biotherapeutics when material availability is …

To achieve the “carbon peaking and carbon neutrality goals”, carbon capture, utilization, and
storage (CCUS) is a research hotspot. In our work, molecular dynamics simulation method is …

Isorhamnetin, kaempferol, myricetin, and quercetin are four kinds of secondary metabolites
in sea buckthorn, which have a wide range of biological activities. Investigating their …

Molecular dynamics (MD) simulations probe the conformational repertoire of
macromolecular systems using Newtonian dynamic equations. The time scales of MD …

The uses of charged poly/oligo-saccharides enable the retarding of protein denaturation
against various environmental stresses during food storage and manufacturing. However, at …

Biopharmaceuticals are labile biomolecules that must be safeguarded to ensure the safety,
quality, and efficacy of the product. Batch freeze-drying is an established means of …

The aims of this work were to evaluate the effect of freezing and thawing stresses on lactate
dehydrogenase (LDH) stability under three conditions.(i) In a solution buffered with sodium …

A continuous manufacturing technology based on coaxial turbulent jet in coflow was
previously developed to produce paclitaxel-loaded polymeric micelles. Herein, coarse …

Natural phytocompounds extensively used in several therapeutic regimes, biomedical and
pharmaceutical applications and their nanoparticles have become extremely essential in …

The characteristics of phytocompounds and essential oils have undergone extensive
research in the medical and pharmaceutical sectors due to their extensive usage. In spite of …