Background and Purpose The SARS‐COV‐2 pandemic and the global spread of
coronavirus disease 2019 (COVID‐19) urgently call for efficient and safe antiviral treatment …

Posaconazole is often used for the prophylaxis and treatment of invasive fungal infections
(IFI). However, intra-and inter-individual differences and drug interactions affect the efficacy …

These updated guidelines from the American Society of Transplantation Infectious Diseases
Community of Practice provide recommendations for the diagnosis and management of …

Second-generation triazoles were developed in response to the quest for more efficacious
and safer therapeutic options for the treatment of severe systemic aspergillosis and …

Introduction Terbinafine is considered the gold standard for treating skin fungal infections
and onychomycosis. However, recent reports suggest that dermatophytes are developing …

Background Posaconazole (PCZ) is used prophylactically to prevent invasive fungal
infections (IFIs) in patients with hematological malignancies. Objective To evaluate the cut …

Posaconazole (PCZ) is effective in preventing and salvage treatment invasive fungal
infections in patients with hematologic disorders. However, PCZ displays highly variable …

The prevalence of obesity has increased considerably in the last few decades.
Pathophysiological changes in obese patients lead to pharmacokinetic (PK) and …

What is known and objective Posaconazole is the second‐generation triazole antifungal
agent with widespread clinical application. Posaconazole exposure is influenced by various …

Background Posaconazole delayed-release tablets offer better bioavailability than the liquid
suspension, but no post-marketing data are available in immunocompetent hosts such as …