In vivo, contactless, cellular resolution imaging of the human cornea with Powell lens based line field OCT

K Chen, N Abbasi, A Wong, K Bizheva - Scientific Reports, 2024 - nature.com
Potentially blinding corneal diseases alter the morphology of the human cornea. At the early
stages of disease development, these changes occur at the cellular level. The ability to …

Real-time line-field optical coherence tomography for cellular resolution imaging of biological tissue

K Neuhaus, S Khan, O Thaware, S Ni, M Aga… - Biomedical Optics …, 2024 - opg.optica.org
A real-time line-field optical coherence tomography (LF-OCT) system is demonstrated with
image acquisition rates of up to 5000 B-frames or 2.5 million A-lines per second for 500 A …

Rapid imaging and product screening with low-cost line-field Fourier domain optical coherence tomography

Z Zhang, X Yang, Z Zhao, F Zeng, S Ye, SJ Baldock… - Scientific reports, 2023 - nature.com
Fourier domain optical coherence tomography (FD-OCT) is a well-established imaging
technique that provides high-resolution internal structure images of an object at a fast speed …

Computational approach for correcting defocus and suppressing speckle noise in line-field optical coherence tomography images

N Abbasi, K Chen, A Wong, K Bizheva - Biomedical Optics Express, 2024 - opg.optica.org
The trade-off between transverse resolution and depth-of-focus (DOF) typical for optical
coherence tomography (OCT) systems based on conventional optics, prevents “single-shot” …

Cellular structural and functional imaging of donor and pathological corneas with label-free dual-mode full-field optical coherence tomography

K Fei, Z Luo, Y Chen, Y Huang, S Li… - Biomedical Optics …, 2024 - opg.optica.org
In this study, a dual-mode full-field optical coherence tomography (FFOCT) was customized
for label-free static and dynamic imaging of corneal tissues, including donor grafts and …

[HTML][HTML] Comparison of Line-Focused and Point-Focused Raman Mineral Analysis in Planetary Exploration

M Wang, C Wang, P Liu, H Qu, Z Ling - Remote Sensing, 2024 - mdpi.com
Raman spectroscopy plays a critical role in planetary exploration by providing detailed
analysis of mineralogical and chemical compositions. However, the conventional point …

Line-field dynamic optical coherence tomography platform for volumetric assessment of biological tissues

K Chen, S Swanson, K Bizheva - Biomedical Optics Express, 2024 - opg.optica.org
Dynamic optical coherence tomography (dOCT) utilizes time-dependent signal intensity
fluctuations to enhance contrast in OCT images and indirectly probe physiological …

High-speed low-cost line-field spectral-domain optical coherence tomography for industrial applications

X Yang, Z Zhang, X Li, H Lin, S Lawman… - Optics and Lasers in …, 2025 - Elsevier
Abstract The applications of Optical Coherence Tomography (OCT) systems have been
extensively explored in clinical settings and have attracted growing interest in other fields …

Powell lens-based Line-Field OCT for in-vivo, contact-less, cellular resolution imaging of the human cornea

K Chen, N FIROOZJAH, A Wong, K Bizheva - 2024 - preprints.opticaopen.org
Potentially blinding corneal diseases alter the morphology of the human cornea. At the early
stages of disease development, these changes occur at cellular level. The ability to visualize …

30 Years of Optical Coherence Tomography: introduction to the feature issue

RA Leitgeb, B Bouma, K Grieve, C Hendon… - Biomedical optics …, 2023 - opg.optica.org
30 Years of Optical Coherence Tomography: introduction to the feature issue clickable element
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