Progressive massive fibrosis: An overview of the recent literature

DN Weissman - Pharmacology & therapeutics, 2022 - Elsevier
This review provides an overview of literature addressing progressive massive fibrosis
(PMF) from September 2009 to the present. Advances are described in understanding its …

From basic research to clinical practice: considerations for treatment drugs for silicosis

R Li, H Kang, S Chen - International Journal of Molecular Sciences, 2023 - mdpi.com
Silicosis, characterized by irreversible pulmonary fibrosis, remains a major global public
health problem. Nowadays, cumulative studies are focusing on elucidating the pathogenesis …

Demographic, exposure and clinical characteristics in a multinational registry of engineered stone workers with silicosis

JT Hua, L Zell-Baran, LHT Go, MR Kramer… - Occupational and …, 2022 - oem.bmj.com
Objectives To investigate differences in workplace exposure, demographic and clinical
findings in engineered stone (ES) workers from a multinational consortium using the …

[HTML][HTML] Content of crystalline silica phases in porcelain stoneware

C Molinari, S Conte, M Dondi, C Zanelli - Open Ceramics, 2024 - Elsevier
Kitchen and bathroom countertop is a demanding application, where high aesthetic
standards must combine with durability, ease of maintenance, and resistance to heat, stain …

Understanding the pathogenesis of engineered stone‐associated silicosis: The effect of particle chemistry on the lung cell response

C Ramkissoon, Y Song, S Yen, K Southam… - …, 2024 - Wiley Online Library
Abstract Background and Objective The resurgence of severe and progressive silicosis
among engineered stone benchtop industry workers is a global health crisis. We …

LGALS3 regulates endothelial-to-mesenchymal transition via PI3K/AKT signaling pathway in silica-induced pulmonary fibrosis

D Cheng, W Lian, X Jia, T Wang, W Sun, Y Liu, C Ni - Toxicology, 2024 - Elsevier
Silicosis is a progressive and chronic occupational lung disease characterized by lung
inflammation, silicotic nodule formation, and diffuse pulmonary fibrosis. Emerging evidence …

The role of pathologists in the diagnosis of occupational lung diseases: an expert opinion of the European Society of Pathology Pulmonary Pathology Working Group

F Calabrese, MA Montero-Fernandez, I Kern, F Pezzuto… - Virchows Archiv, 2024 - Springer
Occupational lung/thoracic diseases are a major global public health issue. They comprise a
diverse spectrum of health conditions with complex pathology, most of which arise following …

Inflammatory indices obtained from routine blood tests show an inflammatory state associated with disease progression in engineered stone silicosis patients

A García-Núñez, G Jiménez-Gómez… - Scientific reports, 2022 - nature.com
Patients with silicosis caused by occupational exposure to engineered stone (ES) present a
rapid progression from simple silicosis (SS) to progressive massive fibrosis (PMF). Patient …

Engineering Macrophage‐Derived Exosome to Deliver Pirfenidone: A Novel Approach to Combat Silicotic Pulmonary Fibrosis

Z Chen, X Yun, J Tian, F Li, Z Zhang… - Advanced …, 2024 - Wiley Online Library
Silicosis is a severe lung disease characterized by diffuse pulmonary fibrosis, for which
there is currently no effective treatment. Pirfenidone (PFD) shows great antifibrotic potential …

Engineered stone fabrication work releases volatile organic compounds classified as lung irritants

C Ramkissoon, S Gaskin, T Hall… - Annals of Work …, 2023 - academic.oup.com
Engineered stones are often characterized for their crystalline silica content. Their organic
composition, particularly that of the emissions generated during fabrication work using hand …