Delirium in ICU patients is a complication associated with many adverse consequences.
Given the high prevalence of this complication in critically ill patients, it is essential to …

Delirium occurs in critical illness and is associated with poor clinical outcomes, having a
longstanding impact on survivors. Understanding the complexity of delirium in critical illness …

Background Sepsis is a global health problem with high morbidity and mortality. Low-and
middle-income countries have a higher incidence and poorer outcome with sepsis. Large …

Abstract Background &Aims: Thiamine is an essential micronutrient for energy metabolism.
Thiamine deficiency is frequently observed in critically ill patients. However, the effect of …

Zusammenfassung Dieses zweite Positionspapier der Sektion Metabolismus und Ernährung
der Deutschen Interdisziplinären Vereinigung für Intensiv-und Notfallmedizin (DIVI) gibt …

Sepsis is a clinical syndrome characterised by a severe disorder of pathophysiology caused
by infection of pathogenic micro-organisms. The addition of antioxidant micronutrient …

Background Thiamine di-phosphate is an essential cofactor in glucose metabolism,
glutamate transformation and acetylcholinesterase activity, pathways associated with …

Vitamin C-based cluster therapy, which involves the combined application of hydrocortisone,
vitamin C, and thiamine (HAT), is a recently proposed new treatment option for sepsis on top …

Objective To determine the normal reference interval (RI) for thiamine concentrations in
healthy dogs and investigate the prevalence of thiamine deficiency in critically ill dogs with …

In critical illness, homeostatic corrections, which represent the culmination of hundreds of
millions of years of evolution, are primarily regulated by the glucocorticoid (GC)-activated …