Hereditary angioedema is a rare inherited disorder characterized by recurrent episodes of
the accumulation of fluids outside of the blood vessels, causing rapid swelling of tissues in …

More recently, HAE has been identified in patients who present with normal C1-INH levels
and activity, classified as HAE with normal C1-INH (previously known as type III HAE). 9 …

Background Hereditary angioedema (HAE) with C1-inhibitor deficiency is associated with
painful, potentially fatal attacks affecting subcutaneous or submucosal tissues. Objective To …

Background Berotralstat (BCX7353) is an oral, once‐daily inhibitor of plasma kallikrein
recently approved for prevention of angioedema attacks in adults and adolescents with …

Background This systematic study aims to assess the global epidemiologic, economic, and
humanistic burden of illness associated with all types of hereditary angioedema. Methods A …

Hereditary angioedema (HAE) is an uncommon genetic disorder characterized by recurrent
episodes of edema involving subcutaneous tissue and submucosa. The pathogenesis of …

Background Hereditary angioedema (HAE) is a rare genetic disease with significant
morbidity and mortality for which early diagnosis and effective therapy are critical. Many Asia …

Hereditary angioedema (HAE) was first described by Dinkelacker 1 and Quincke 2 in 1882
and a few years later by Osler 3 as recurrent angioedema with a positive family history. In …

Hereditary angioedema (HAE) due to C1-inhibitor (C1-INH) deficiency or dysfunction is a
rare genetic disorder that causes recurrent episodes of swelling in various parts of the body …

Background Hereditary angioedema (HAE) is often caused by low serum levels or functional
deficiency in C1 inhibitor (C1-INH); however, in some cases, C1-INH serum level and …