Pseudomonas aeruginosa is an opportunistic pathogen that synthesizes and secretes a
wide range of virulence factors. P. aeruginosa poses a potential threat to human health …

In contrast to planktonic cells, bacteria imbedded biofilms are notoriously refractory to
treatment by antibiotics or bacteriophage (phage) used alone. Given that the mechanisms of …

The opportunistic pathogen Pseudomonas aeruginosa employs the type III secretion system
(T3SS) and four effector proteins, ExoS, ExoT, ExoU, and ExoY, to disrupt cellular …

Pseudomonas aeruginosa (P. aeruginosa) possesses a plethora of virulence determinants,
including the production of biofilm, pigments, exotoxins, proteases, flagella, and secretion …

Introduction Bloodstream infections are associated with high mortality rates and contribute
substantially to healthcare costs, but a consensus on the prognostic benefits of appropriate …

Antimicrobial resistance is a major threat to global public health. Vaccination is an effective
approach for preventing bacterial infections, however it has not been successfully applied to …

Abstract Objectives Treating infections of Gram-negative pathogens, in particular
Pseudomonas aeruginosa, is a challenge for clinicians in the Asia-Pacific region owing to …

CbrAB is a two-component system, unique to bacteria of the family Pseudomonaceae,
capable of integrating signals and involved in a multitude of physiological processes that …

Pseudomonas aeruginosa is a serious pathogen particularly in immunocompromised
patients. In this work, 103 clinical isolates of P. aeruginosa were collected and classified into …

In the context of pulmonary infection, both hosts and pathogens have evolved a multitude of
mechanisms to regulate the process of host cell death. The host aims to rapidly induce an …