Mammalian genomes are pervasively transcribed, to produce thousands of long non-coding
RNAs (lncRNAs),. A few of these lncRNAs have been shown to recruit regulatory complexes …

Nature increases the functional diversity of the proteome through posttranslational
modifications (PTMs); a process that involves the proteolytic processing or catalytic …

Nucleotide modifications constitute marks in RNA and DNA that contribute to gene
regulation, development and other cellular processes. The understanding of their intricate …

Rapid, inexpensive, and easy-to-use coronavirus disease 2019 (COVID-19) home tests are
key tools in addition to vaccines in the world wide fight to eliminate national and local …

Gene expression is orchestrated by transcription factors, which function within the context of
a three-dimensional genome. Zinc-finger protein 143 (ZNF143/ZFP143) is a transcription …

Lysine dimethylation (Kme2) is a crucial post-translational modification (PTM) that regulates
biological processes and is implicated in diseases. There is significant interest in globally …

Generating recombinant monoclonal antibodies (R-mAbs) from mAb-producing hybridomas
offers numerous advantages that increase the effectiveness, reproducibility, and transparent …

It has been shown that SARS-CoV-2 shares homology and cross-reacts with vaccines, other
viruses, common bacteria and many human tissues. We were inspired by these findings …

Chromatin marks are associated with transcriptional regulatory activities. However, very few
lncRNAs have been characterized with the role in regulating epigenetic marks, largely due …

BET-bromodomain inhibition (BETi) has shown pre-clinical promise for MYC-amplified
medulloblastoma. However, the mechanisms for its action, and ultimately for resistance …