The machineries, regulation and cellular functions of mitochondrial calcium

C Giorgi, S Marchi, P Pinton - Nature reviews Molecular cell biology, 2018 - nature.com
Abstract Calcium ions (Ca2+) are some of the most versatile signalling molecules, and they
have many physiological functions, prominently including muscle contraction, neuronal …

Short overview of ROS as cell function regulators and their implications in therapy concepts

L Milkovic, A Cipak Gasparovic, M Cindric, PA Mouthuy… - Cells, 2019 - mdpi.com
The importance of reactive oxygen species (ROS) has been gradually acknowledged over
the last four decades. Initially perceived as unwanted products of detrimental oxidative …

[HTML][HTML] Mitochondria: Their relevance during oocyte ageing

J van der Reest, GN Cecchino, MC Haigis… - Ageing research …, 2021 - Elsevier
The oocyte is recognised as the largest cell in mammalian species and other multicellular
organisms. Mitochondria represent a high proportion of the cytoplasm in oocytes and …

Mitochondrial dysfunction and oxidative stress caused by cryopreservation in reproductive cells

R Gualtieri, G Kalthur, V Barbato, M Di Nardo, SK Adiga… - Antioxidants, 2021 - mdpi.com
Mitochondria, fundamental organelles in cell metabolism, and ATP synthesis are
responsible for generating reactive oxygen species (ROS), calcium homeostasis, and cell …

Calcium dynamics as a machine for decoding signals

C Giorgi, A Danese, S Missiroli, S Patergnani… - Trends in cell …, 2018 - cell.com
Calcium (Ca 2+) is considered one of the most-important biological cations, because it is
implicated in cell physiopathology and cell fate through a finely tuned signaling system. In …

Persistence and recovery of ZIF-8 and ZIF-67 phytotoxicity

X Zhang, X Hu, H Wu, L Mu - Environmental Science & …, 2021 - ACS Publications
Zeolitic imidazolate frameworks (ZIFs) have been developed quickly and have attracted
considerable attention for use in the detection and removal of various pollutants …

Revisiting the role of metabolism during development

H Miyazawa, A Aulehla - Development, 2018 - journals.biologists.com
An emerging view emphasizes that metabolism is highly regulated in both time and space.
In addition, it is increasingly being recognized that metabolic pathways are tightly connected …

Role of food antioxidants in modulating gut microbial communities: Novel understandings in intestinal oxidative stress damage and their impact on host health

MS Riaz Rajoka, R Thirumdas, HM Mehwish, M Umair… - Antioxidants, 2021 - mdpi.com
Dietary components have an important role on the structure and function of host gut
microbial communities. Even though, various dietary components, such as carbohydrates …

Mitophagy and reactive oxygen species interplay in Parkinson's disease

B Xiao, J Kuruvilla, EK Tan - npj Parkinson's Disease, 2022 - nature.com
Mitophagy impairment and oxidative stress are cardinal pathological hallmarks in
Parkinson's disease (PD), a common age-related neurodegenerative condition. The specific …

[HTML][HTML] Acetaldehyde induces phosphorylation of dynamin-related protein 1 and mitochondrial dysfunction via elevating intracellular ROS and Ca2+ levels

T Yan, Y Zhao - Redox biology, 2020 - Elsevier
Excessive alcohol consumption impairs brain function and has been associated with an
earlier onset of neurodegenerative diseases such as Alzheimer's disease (AD) and …