Thousands of previously unknown phages discovered in whole-community human gut metagenomes
Background Double-stranded DNA bacteriophages (dsDNA phages) play pivotal roles in
structuring human gut microbiomes; yet, the gut virome is far from being fully characterized …
structuring human gut microbiomes; yet, the gut virome is far from being fully characterized …
Characterization of crAss-like phage isolates highlights Crassvirales genetic heterogeneity and worldwide distribution
MD Ramos-Barbero, C Gómez-Gómez… - Nature …, 2023 - nature.com
Crassvirales (crAss-like phages) are an abundant group of human gut-specific
bacteriophages discovered in silico. The use of crAss-like phages as human fecal indicators …
bacteriophages discovered in silico. The use of crAss-like phages as human fecal indicators …
Towards an integrative view of virus phenotypes
Understanding how phenotypes emerge from genotypes is a foundational goal in biology.
As challenging as this task is when considering cellular life, it is further complicated in the …
As challenging as this task is when considering cellular life, it is further complicated in the …
Reclassification of family A DNA polymerases reveals novel functional subfamilies and distinctive structural features
D Czernecki, A Nourisson, P Legrand… - Nucleic Acids …, 2023 - academic.oup.com
Abstract Family A DNA polymerases (PolAs) form an important and well-studied class of
extant polymerases participating in DNA replication and repair. Nonetheless, despite the …
extant polymerases participating in DNA replication and repair. Nonetheless, despite the …
Interaction dynamics and virus–host range for estuarine actinophages captured by epicPCR
Viruses impact microbial diversity, gene flow and function through virus–host interactions.
Although metagenomics surveys are rapidly cataloguing viral diversity, methods are needed …
Although metagenomics surveys are rapidly cataloguing viral diversity, methods are needed …
Benchmarking bioinformatic virus identification tools using real-world metagenomic data across biomes
Background As most viruses remain uncultivated, metagenomics is currently the main
method for virus discovery. Detecting viruses in metagenomic data is not trivial. In the past …
method for virus discovery. Detecting viruses in metagenomic data is not trivial. In the past …
Climate-endangered Arctic epishelf lake harbors viral assemblages with distinct genetic repertoires
Milne Fiord, located on the coastal margin of the Last Ice Area (LIA) in the High Arctic (82° N,
Canada), harbors an epishelf lake, a rare type of ice-dependent ecosystem in which a layer …
Canada), harbors an epishelf lake, a rare type of ice-dependent ecosystem in which a layer …
Abundant and cosmopolitan lineage of cyanopodoviruses lacking a DNA polymerase gene
Cyanopodoviruses affect the mortality and population dynamics of the unicellular
picocyanobacteria Prochlorococcus and Synechococcus, the dominant primary producers in …
picocyanobacteria Prochlorococcus and Synechococcus, the dominant primary producers in …
DNA polymerase swapping in Caudoviricetes bacteriophages
N Yutin, I Tolstoy, P Mutz, YI Wolf, M Krupovic… - Virology Journal, 2024 - Springer
Background Viruses with double-stranded (ds) DNA genomes in the realm Duplodnaviria
share a conserved structural gene module but show a broad range of variation in their …
share a conserved structural gene module but show a broad range of variation in their …
Genomic diversity and biogeographic distributions of a novel lineage of bacteriophages that infect marine OM43 bacteria
M Yang, S Du, Z Zhang, Q Xia, H Liu, F Qin… - Microbiology …, 2023 - Am Soc Microbiol
The marine methylotrophic OM43 clade is considered an important bacterial group in
coastal microbial communities. OM43 bacteria, which are closely related to phytoplankton …
coastal microbial communities. OM43 bacteria, which are closely related to phytoplankton …