Understanding radiation‐induced non‐cancer effects on the central nervous system (CNS)
is essential for the risk assessment of medical (eg, radiotherapy) and occupational (eg …

With new and advanced technology, human exploration has reached outside of the Earth's
boundaries. There are plans for reaching Mars and the satellites of Jupiter and Saturn, and …

Breast cancer susceptibility gene 1 (BRCA1) is a breast and ovarian cancer tumor
suppressor whose loss leads to DNA damage and defective centrosome functions. Despite …

There is accumulating clinical evidence that chemotherapeutic agents induce neurological
side effects, including memory deficits and mood disorders, in cancer patients who have …

During orbital or interplanetary space flights, astronauts are exposed to cosmic radiations
and microgravity. However, most earth-based studies on the potential health risks of space …

X-ray irradiation (X-irradiation) induces disruption of the blood–brain barrier (BBB).
However, the mechanisms underlying the permeability changes are unclear. Therefore, in …

Neurons are essential components of neural circuits and provide brain function
organization. We previously reported that X irradiation induces apoptosis in immature …

There has been a substantial amount of research on the relationship between hippocampal
neurogenesis and behaviour over the past fifteen years, but the causal role that new …

The effects of X-irradiation on developing neurons and their functions are unclear. We used
primary cultures of mouse hippocampal neurons to investigate the effects of X-irradiation on …

Non‑proliferating cells, such as mature neurons, are generally believed to be more resistant
to X‑rays than proliferating cells, such as glial and vascular endothelial cells. Therefore, the …