Covering: 2015. Previous review: Nat. Prod. Rep., 2016, 33, 382–431 This review covers the
literature published in 2015 for marine natural products (MNPs), with 1220 citations (792 for …

Genomic data often highlights an inconsistency between the number of gene clusters
identified using bioinformatic approaches as potentially producing secondary metabolites …

Microbial secondary metabolites (MSMs) have played and continue to play a highly
significant role in the drug discovery and development process. Genetically, MSM chemical …

Natural products derived from marine microorganisms have received great attention as a
potential resource of new compound entities for drug discovery. The unique marine …

Twelve new cytochalasins, phomopchalasins D–O (1–3, 5–12, and 14), including one
brominated (2) and two iodinated cytochalasins (3 and 6), together with six known …

Marine microorganisms have proven to be a source of new natural products with a wide
spectrum of biological activities relevant in different industrial sectors. The ever-increasing …

This review covers the literature published in 2015 for marine natural products (MNPs), with
1220 citations (792 for the period January to December 2015) referring to compounds …

A new epidithiodiketopiperazine (ETP), pretrichodermamide G (1), along with three known
(epi) dithiodiketopiparazines (2-4) were isolated from cultures of Trichoderma harzianum …

Cyclodipeptides, called 2, 5-diketopiperazines (2, 5-DKPs), are obtained by the
condensation of two amino acids. Fungi have been considered to be a rich source of novel …

Strategies to single-step edit the core skeleton of structurally complex compounds still
remains highly desirable but challenging. Herein an unexpected discovery to access natural …