Promising epigenetic biomarkers for the early detection of colorectal cancer: a systematic review
SA Anghel, CB Ioniță-Mîndrican, I Luca, AL Pop - Cancers, 2021 - mdpi.com
Simple Summary High-performance, non-invasive screening is a requirement in colorectal
cancer (CRC) as early detection is a key in reducing disease-related mortality in CRC …
cancer (CRC) as early detection is a key in reducing disease-related mortality in CRC …
Advances in blood DNA methylation-based assay for colorectal cancer early detection: a systematic updated review
M Khabbazpour, M Tat, A Karbasi… - … from Bed to Bench, 2024 - pmc.ncbi.nlm.nih.gov
Aim: A systematic review was conducted to summarize the methylated circulating tumor DNA
(ctDNA) markers reported over the last decade for early detection of colorectal cancer (CRC) …
(ctDNA) markers reported over the last decade for early detection of colorectal cancer (CRC) …
Highlighting transcribed ultraconserved regions in human diseases
E Pereira Zambalde, C Mathias… - Wiley …, 2020 - Wiley Online Library
Ultraconserved regions (UCRs) are 481 DNA segments longer than 200 bp in length that
are completely conserved among human, mouse, and rat and, extremely conserved across …
are completely conserved among human, mouse, and rat and, extremely conserved across …
Transcribed Ultraconserved Regions: New regulators in cancer signaling and potential biomarkers
JC Oliveira - Genetics and molecular biology, 2023 - SciELO Brasil
The ultraconserved regions (UCRs) are 481 genomic elements, longer than 200 bp, 100%
conserved in human, mouse, and rat genomes. Usually, coding regions are more …
conserved in human, mouse, and rat genomes. Usually, coding regions are more …
A transcribed ultraconserved noncoding RNA, uc. 285+, promotes colorectal cancer proliferation through dual targeting of CDC42 by directly binding mRNA and …
S Chen, Q Zhao, R Zhang, J Liu, W Peng, H Xu… - Translational …, 2024 - Elsevier
The transcribed ultraconserved region (T-UCR) belongs to a new type of lncRNAs that are
conserved in homologous regions of the rat, mouse and human genomes. A lot of research …
conserved in homologous regions of the rat, mouse and human genomes. A lot of research …
The transcribed ultraconserved region uc.160+ enhances processing and A‐to‐I editing of the miR‐376 cluster: hypermethylation improves glioma prognosis
M Soler, V Davalos, A Sánchez‐Castillo… - Molecular …, 2022 - Wiley Online Library
Transcribed ultraconserved regions (T‐UCRs) are noncoding RNAs derived from DNA
sequences that are entirely conserved across species. Their expression is altered in many …
sequences that are entirely conserved across species. Their expression is altered in many …
Clinical significance of plasma CD9-positive exosomes in HIV seronegative and seropositive lung cancer patients
FI Dimitrakopoulos, AE Kottorou, K Rodgers… - Cancers, 2021 - mdpi.com
Simple Summary The role of exosomes in HIV (human immunodeficiency virus) as well as in
cancer patients seems to be pivotal. The aim of our retrospective study was to assess the …
cancer patients seems to be pivotal. The aim of our retrospective study was to assess the …
The transcribed-ultra conserved regions: novel non-coding RNA players in neuroblastoma progression
N Mudgapalli, BP Shaw, S Chava, KB Challagundla - Non-coding RNA, 2019 - mdpi.com
The Transcribed-Ultra Conserved Regions (T-UCRs) are a class of novel non-coding RNAs
that arise from the dark matter of the genome. T-UCRs are highly conserved between …
that arise from the dark matter of the genome. T-UCRs are highly conserved between …
Differentially methylated ultra-conserved regions Uc160 and Uc283 in adenomas and adenocarcinomas are associated with overall survival of colorectal cancer …
AE Kottorou, FID Dimitrakopoulos, AG Antonacopoulou… - Cancers, 2020 - mdpi.com
Deregulation of the transcribed ultra-conserved regions (T-UCRs) Uc160, Uc283, and
Uc346 has been reported in colorectal cancer (CRC) recently. Here, we investigated …
Uc346 has been reported in colorectal cancer (CRC) recently. Here, we investigated …
The dark matter of the human genome and its role in human cancers
I Bozgeyik - Gene, 2022 - Elsevier
The transcribed ultra-conserved regions (T-UCRs) are a novel family of non-coding RNAs
which are absolutely conserved (100%) across orthologous regions of the human, mouse …
which are absolutely conserved (100%) across orthologous regions of the human, mouse …