Tissue fibrosis induced by radiotherapy: current understanding of the molecular mechanisms, diagnosis and therapeutic advances

Z Yu, C Xu, B Song, S Zhang, C Chen, C Li… - Journal of Translational …, 2023 - Springer
Cancer remains the leading cause of death around the world. In cancer treatment, over 50%
of cancer patients receive radiotherapy alone or in multimodal combinations with other …

Molecular and cellular mechanisms associated with effects of molecular hydrogen in cardiovascular and central nervous systems

M Barancik, B Kura, TW LeBaron, R Bolli, J Buday… - Antioxidants, 2020 - mdpi.com
The increased production of reactive oxygen species and oxidative stress are important
factors contributing to the development of diseases of the cardiovascular and central …

Synthesis and iodine adsorption properties of organometallic copolymers with propeller-shaped Fe (II) clathrochelates bridged by different diaryl thioether and their …

S Shetty, N Baig, B Alameddine - Polymers, 2022 - mdpi.com
Three organometallic copolymers, ICP1-3, containing iron (II) clathrochelate units with
cyclohexyl lateral groups and interconnected by various thioether derivatives were …

DAMPs and radiation injury

S Yamaga, M Aziz, A Murao, M Brenner… - Frontiers in …, 2024 - frontiersin.org
The heightened risk of ionizing radiation exposure, stemming from radiation accidents and
potential acts of terrorism, has spurred growing interests in devising effective …

Development of radiation countermeasure agents for acute radiation syndromes

B Guan, D Li, A Meng - Animal Models and Experimental …, 2023 - Wiley Online Library
The risk of internal and external exposure to ionizing radiation (IR) has increased alongside
the development and implementation of nuclear technology. Therefore, serious security …

Monophosphoryl lipid A ameliorates radiation-induced lung injury by promoting the polarization of macrophages to the M1 phenotype

X Guo, L Du, N Ma, P Zhang, Y Wang, Y Han… - Journal of Translational …, 2022 - Springer
Background Radiation-induced lung injury (RILI) often occurs during clinical chest
radiotherapy and acute irradiation from accidental nuclear leakage. This study explored the …

Sargramostim in acute radiation syndrome

HM Lazarus, J McManus, RP Gale - Expert Opinion on Biological …, 2022 - Taylor & Francis
Introduction Since 1944, nearly 400 radiologic accidents/incidents have exposed about
3,000 people to substantial doses of ionizing radiation, with more than 125 deaths. Known …

Ionizing Radiation, Antioxidant Response and Oxidative Damage: Radiomodulators

E Obrador, A Montoro - Antioxidants, 2023 - mdpi.com
Ionizing radiation (IR) is the energy released by atoms in the form of electromagnetic waves
(eg, X or gamma rays) or particle radiation (alpha, beta, electrons, protons, neutrons …

Health Effects of Ionizing Radiation on the Human Body

J Talapko, D Talapko, D Katalinić, I Kotris, I Erić… - Medicina, 2024 - mdpi.com
Radioactivity is a process in which the nuclei of unstable atoms spontaneously decay,
producing other nuclei and releasing energy in the form of ionizing radiation in the form of …

Tocotrienols Provide Radioprotection to Multiple Organ Systems through Complementary Mechanisms of Antioxidant and Signaling Effects

SA Shrum, U Nukala, S Shrimali, EN Pineda, KJ Krager… - Antioxidants, 2023 - mdpi.com
Tocotrienols have powerful radioprotective properties in multiple organ systems and are
promising candidates for development as clinically effective radiation countermeasures. To …