Anemia and patient blood management in cardiac surgery—literature review and current evidence

A Dhir, DK Tempe - Journal of cardiothoracic and vascular …, 2018 - jcvaonline.com
The prevalence of anemia is high in patients undergoing cardiac surgery. There is enough
evidence that the presence of anemia increases perioperative mortality and morbidity both …

Red blood cell sublethal damage: Hemocompatibility is not the absence of hemolysis

AP McNamee, MJ Simmonds - Transfusion Medicine Reviews, 2023 - Elsevier
Blood is a complex fluid owing to its two-phase suspension of formed cellular elements
within a protein-rich plasma. Vital to its role in distributing nutrients throughout the circulatory …

Impact of surface-area-to-volume ratio, internal viscosity and membrane viscoelasticity on red blood cell deformability measured in isotonic condition

C Renoux, M Faivre, A Bessaa, L Da Costa, P Joly… - Scientific reports, 2019 - nature.com
Osmotic gradient ektacytometry is the gold standard to assess red blood cell (RBC)
deformability. It has been proposed that, when measured in isotonic condition, RBC …

Impaired red blood cell deformability after transfusion of stored allogeneic blood but not autologous salvaged blood in cardiac surgery patients

ON Salaria, VM Barodka, CW Hogue… - Anesthesia & …, 2014 - journals.lww.com
BACKGROUND: Both cardiopulmonary bypass (CPB) and red blood cell (RBC) storage are
associated with detrimental changes in RBC structure and function that may adversely affect …

Microcirculatory perfusion is preserved during off-pump but not on-pump cardiac surgery

NJ Koning, ABA Vonk, MI Meesters, T Oomens… - Journal of cardiothoracic …, 2014 - Elsevier
Objective This study investigated the perioperative course of microcirculatory perfusion in off-
pump compared with on-pump surgery. Additionally, the impact of changes in systemic …

The role of hemorheological factors in cardiovascular medicine

A Toth, J Papp, M Rabai, P Kenyeres… - Clinical …, 2014 - content.iospress.com
Cardiovascular diseases (CVD) are the most frequent cause of death throughout the world.
The coronary vessel system is a special part of the circulation since there is a continuous …

[HTML][HTML] Hematological changes in patients undergoing coronary artery bypass surgery: a prospective study

S Lako, T Dedej, T Nurka, V Ostreni, A Demiraj… - Medical …, 2015 - ncbi.nlm.nih.gov
Objectives: Removal of pro inflammatory stimuli after CABG, wound closure and the
regenerative ability of the bone marrow will ensure a gradual recovery of hematological …

Blood-device interaction

MJ Simmonds, N Watanabe, D Nandakumar… - … and respiratory support, 2018 - Elsevier
Management of organ failure has improved in recent years in parallel with advancements in
interventions, including organ transplant, although the shortage of donor organs remains the …

Ex vivo assessment of erythrocyte tolerance to the HeartWare ventricular assist device operated in three discrete configurations

L Kuck, MJ Simmonds, CHH Chan, JP Pauls… - Artificial …, 2021 - Wiley Online Library
Despite technological advances in ventricular assist devices (VADs) to treat end‐stage heart
failure, hemocompatibility remains a constant concern, with supraphysiological shear …

The impact of circulation in a heart–lung machine on function and survival characteristics of red blood cells

J Freitas Leal, H Vermeer, D Lazari… - Artificial …, 2020 - Wiley Online Library
Extracorporeal circulation is accompanied by changes in red blood cell morphology and
structural integrity that affect cell function and survival, and thereby may contribute to the …