Advanced Application of Polymer Nanocarriers in Delivery of Active Ingredients from Traditional Chinese Medicines

Z Zhai, J Niu, L Xu, J Xu - Molecules, 2024 - pmc.ncbi.nlm.nih.gov
Active ingredients from Traditional Chinese Medicines (TCMs) have been a cornerstone of
healthcare for millennia, offering a rich source of bioactive compounds with therapeutic …

AP3B1 facilitates PDIA3/ERP57 function to regulate rabies virus glycoprotein selective degradation and viral entry

Y Zhang, X Zhang, X Yang, L Lv, Q Wang, S Zeng… - Autophagy, 2024 - Taylor & Francis
Rabies virus causes an estimated 59,000 annual fatalities worldwide and promising
therapeutic treatments are necessary to develop. In this study, affinity tag-purification mass …

[HTML][HTML] Integrating transcriptomic and proteomic data for a comprehensive molecular perspective on the association between sarcopenia and osteoporosis

J Chen, J Xu, L Gou, Y Zhu, W Zhong, H Guo… - Archives of Gerontology …, 2024 - Elsevier
Background Osteoporosis and sarcopenia are common age-related conditions
characterized by the progressive loss of bone density and muscle mass, respectively. Their …

[HTML][HTML] A Global Identification of Protein Disulfide Isomerases from 'duli'Pear (Pyrus betulaefolia) and Their Expression Profiles under Salt Stress

H Zhang, Y Zhang, K Cui, C Liu, M Chen, Y Fu, Z Li… - Genes, 2024 - pmc.ncbi.nlm.nih.gov
Protein disulfide isomerases (PDIs) and PDI-like proteins catalyze the oxidation and
reduction in protein disulfide bonds, inhibit aggregation of misfolded proteins, and …

Opposed regulation of endoplasmic reticulum retention under stress by ERp44 and PDIA6

O Yassin, B Praveen, O Darawshi, T LaFramboise… - 2024 - portlandpress.com
Conditions of endoplasmic reticulum (ER) stress reduce protein synthesis by provoking
translation regulation, governed by the eIF2α kinase PERK. When PERK is inhibited during …

PDIA6 promotes the progression of ESCC via AKT1/mTOR signal pathway by forming disulfide-dependent TRAF4

K Liu, Y Chen, X Li, Y Chen, Y Shi, Q Yuan, R Han… - 2024 - researchsquare.com
Unveiling the underlying mechanism of esophageal squamous cell carcinoma (ESCC) is
particularly valuable for discovering new therapeutic targets. The AKT1/mTOR pathway is a …