DNA is the molecule that stores and transmits genetic information in biological systems. The
field of DNA nanotechnology takes this molecule out of its biological context and uses its …

The comprehensive understanding and proper use of supramolecular interactions have
become critical for the development of functional materials, and so is the biomedical …

We report a spherical nucleic acid (SNA) system for the delivery of BKM120, an anticancer
drug for treatment of chronic lymphocytic leukemia (CLL). While promising for cancer …

Abstract Two‐dimensional (2D) assemblies of water‐soluble block copolymers have been
limited by a dearth of systematic studies that relate polymer structure to pathway mechanism …

Supramolecular one-dimensional (1D) architectures are of high interest in drug delivery and
templation of complex linear arrays due to their high aspect ratio and rigidity. A particular …

DNA nanostructures with different sizes and shapes, assembled through either covalent or
non-covalent bonds, namely tetrahedral and octahedral nanocages, rod-shaped chainmails …

Triggering the release of small molecules in response to unique biomarkers is important for
applications in drug delivery and biodetection. Due to low quantities of biomarker, amplifying …

Drug delivery vectors for nucleic acid therapeutics (NATs) face significant barriers for
translation into the clinic. Spherical nucleic acids (SNAs)–nanoparticles with an exterior …

Nucleic acid therapeutics (NATs), such as mRNA, small interfering RNA or antisense
oligonucleotides are extremely efficient tools to modulate gene expression and tackle …

Biopolymers such as nucleic acids and proteins exhibit dynamic backbone folding, wherein
site-specific intramolecular interactions determine overall structure. Proteins then …