Body fluids are constantly replenished with a population of genetically diverse cell-free DNA
(cfDNA) fragments, representing a vast reservoir of information reflecting real-time changes …

Immunothrombosis is a potentially beneficial physiological process that aids innate immunity
and host defense against pathogen invasion. However, this process can also be damaging …

Genomic and precision medicine research has afforded notable advances in human cancer
treatment, yet applicability to other species remains uncertain. Through whole-exome and …

Purpose: Chromosomal instability is a fundamental property of cancer, which can be
quantified by next-generation sequencing (NGS) from plasma/serum–derived cell-free DNA …

Spontaneously occurring canine mammary cancer represents an excellent model of human
breast cancer, but is greatly understudied. To better use this valuable resource, we …

Cancer is the leading cause of death in dogs, in part because many cases are identified at
an advanced stage when clinical signs have developed, and prognosis is poor. Increased …

The animal's blood is the most complicated and important biological liquid for veterinary
medicine. In addition to standard methods that are always in use, recent technologies such …

The correct folding is a key process for a protein to acquire its functional structure and
conformation. Prefoldin is a well-known chaperone protein that regulates the correct folding …

This proof-of-concept study demonstrates that blood-based liquid biopsy using next
generation sequencing of cell-free DNA can non-invasively detect multiple classes of …

Objectives To determine if cell‐free DNA (cfDNA) was identifiable in canine plasma, to
evaluate 3 techniques for the measurement of plasma cfDNA concentrations in dogs …