The molecular basis of erythrocyte invasion by malaria parasites

AF Cowman, CJ Tonkin, WH Tham, MT Duraisingh - Cell host & microbe, 2017 - cell.com
Plasmodium species cause malaria by proliferating in human erythrocytes. Invasion of
immunologically privileged erythrocytes provides a relatively protective niche as well as …

[HTML][HTML] Soft X‐ray tomograms provide a structural basis for whole‐cell modeling

V Loconte, JH Chen, B Vanslembrouck… - The FASEB …, 2023 - ncbi.nlm.nih.gov
Developing in silico models that accurately reflect a whole, functional cell is an ongoing
challenge in biology. Current efforts bring together mathematical models, probabilistic …

PCRCR complex is essential for invasion of human erythrocytes by Plasmodium falciparum

SW Scally, T Triglia, C Evelyn, BA Seager… - Nature …, 2022 - nature.com
The most severe form of malaria is caused by Plasmodium falciparum. These parasites
invade human erythrocytes, and an essential step in this process involves the ligand PfRh5 …

Wrapping anisotropic microgel particles in lipid membranes: Effects of particle shape and membrane rigidity

X Liu, T Auth, N Hazra, MF Ebbesen… - Proceedings of the …, 2023 - National Acad Sciences
Cellular engulfment and uptake of macromolecular assemblies or nanoparticles via
endocytosis can be associated to both healthy and disease-related biological processes as …

20S proteasomes secreted by the malaria parasite promote its growth

E Dekel, D Yaffe, I Rosenhek-Goldian… - Nature …, 2021 - nature.com
Mature red blood cells (RBCs) lack internal organelles and canonical defense mechanisms,
making them both a fascinating host cell, in general, and an intriguing choice for the deadly …

Membrane-mediated interactions between nonspherical elastic particles

J Midya, T Auth, G Gompper - ACS nano, 2023 - ACS Publications
The transport of particles across lipid-bilayer membranes is important for biological cells to
exchange information and material with their environment. Large particles often get wrapped …

4D analysis of malaria parasite invasion offers insights into erythrocyte membrane remodeling and parasitophorous vacuole formation

ND Geoghegan, C Evelyn, LW Whitehead… - Nature …, 2021 - nature.com
Host membrane remodeling is indispensable for viruses, bacteria, and parasites, to subvert
the membrane barrier and obtain entry into cells. The malaria parasite Plasmodium spp …

Host–parasite interactions that guide red blood cell invasion by malaria parasites

AS Paul, ES Egan, MT Duraisingh - Current opinion in hematology, 2015 - journals.lww.com
Host–parasite interactions that guide red blood cell invasio... : Current Opinion in
Hematology Host–parasite interactions that guide red blood cell invasion by malaria …

Nano-and microparticles at fluid and biological interfaces

S Dasgupta, T Auth, G Gompper - Journal of Physics: Condensed …, 2017 - iopscience.iop.org
Abstract Systems with interfaces are abundant in both technological applications and
biology. While a fluid interface separates two fluids, membranes separate the inside of …

Reassessing the mechanics of parasite motility and host-cell invasion

I Tardieux, J Baum - Journal of Cell Biology, 2016 - rupress.org
The capacity to migrate is fundamental to multicellular and single-celled life. Apicomplexan
parasites, an ancient protozoan clade that includes malaria parasites (Plasmodium) and …